Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.48 |
| ▸ | PPARG | P37231 | 8/20 | 0.48 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5365643 | 0.85 | PPARA (0.67) | PPARAPPARGFFAR1 | |
| SCHEMBL7068947 | 0.83 | PPARA (0.46) | PPARAPPARGMAPTCA12CA1 | |
| SCHEMBL4073189 | 0.81 | PPARA (0.71) | PPARAPPARG | |
| SCHEMBL4073200 | 0.81 | PPARA (0.71) | PPARAPPARG | |
| SCHEMBL5661358 | 0.78 | MTNR1A (0.41) | RORC | |
| SCHEMBL5365338 | 0.77 | CXCR2 (0.47) | PPARAPPARGFFAR1 | |
| SCHEMBL4076821 | 0.76 | PPARA (0.58) | PPARAPPARGMAPT | |
| SCHEMBL4080386 | 0.76 | PPARA (0.58) | PPARAPPARGMAPT | |
| SCHEMBL4797636 | 0.76 | FFAR1 (0.52) | PPARAPPARGFFAR1 | |
| SCHEMBL13655828 | 0.76 | PPARA (0.47) | PPARAPPARGRORCMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453795-A2 | ESTERS AND AMIDES AS PPAR-ALPHA AGONISTS | Dr. Reddy's Laboratories Ltd. (IN) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003048116-A2 | ESTERS AND AMIDES AS PPAR-ALPHA AGONISTS ____________ | DR. REDDY'S LABORATORIES LTD. (IN) | 2003-06-12 | — | — | WO | disclosed |