Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.65 |
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.64 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.64 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.64 |
| ▸ | LDHA | P00338 | 1/20 | 0.63 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.63 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 7/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | STAT1 | P42224 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | METAP2 | P50579 | 1/20 | 0.53 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.51 |
| ▸ | RAF1 | P04049 | 2/20 | 0.51 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.51 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10852378 | 0.97 | NPC1 (0.61) | NPC1RAB9AGAAALDH1A1KDM4E | |
| SCHEMBL11228706 | 0.89 | ALDH1A1 (0.68) | NPC1RAB9AGAAALDH1A1KDM4E | |
| SCHEMBL11231437 | 0.88 | KDM4E (0.76) | NPC1RAB9AALDH1A1KDM4EPKN1 | |
| SCHEMBL3331253 | 0.86 | ALDH1A1 (0.71) | NPC1RAB9AGAAALDH1A1KDM4E | |
| SCHEMBL23132042 | 0.83 | ALDH1A1 (0.54) | NPC1RAB9AALDH1A1KDM4EPKN1 | |
| SCHEMBL7271262 | 0.83 | ALDH1A1 (0.54) | NPC1RAB9AGAAALDH1A1KDM4E | |
| SCHEMBL7278387 | 0.83 | ALDH1A1 (0.77) | NPC1RAB9AGAAALDH1A1KDM4E | |
| SCHEMBL23753448 | 0.83 | KDM4E (0.54) | NPC1RAB9AGAAALDH1A1KDM4E | |
| SCHEMBL6258260 | 0.83 | ALDH1A1 (0.63) | NPC1RAB9AGAAALDH1A1KDM4E | |
| SCHEMBL9634802 | 0.83 | KDM4E (0.54) | NPC1RAB9AGAAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7256287-B2 | Phenyl-aza-benzimidazole compounds for modulating IgE and inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2007-08-14 | — | — | US | disclosed |
| US-7256287-B2 | Phenyl-aza-benzimidazole compounds for modulating IgE and inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2007-08-14 | — | — | US | disclosed |
| EP-0937075-B1 | New Imidazo- and Oxazolopyridines as Phosphodiesterase Inhibitors. | ALTANA PHARMA AG (DE) | 2003-12-17 | — | — | EP | disclosed |
| EP-0912568-B1 | IMIDAZOPYRIDINES | ALTANA PHARMA AG (DE) | 2002-11-20 | — | — | EP | disclosed |
| US-6306867-B1 | TREATMENT OF RESPIRATORY SYSTEM DISORDERS, TUMOR NECROSIS FACTOR AND LEUKOTRIENES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2001-10-23 | — | — | US | disclosed |
| US-6172074-B1 | TREATING SKIN AND RESPIRATORY SYSTEM DISORDERS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2001-01-09 | — | — | US | disclosed |
| EP-0937075-A1 | NEW IMIDAZOPYRIDINES AND OXAZOLOPYRIDINES | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1999-08-25 | — | — | EP | disclosed |
| EP-0912568-A1 | NOVEL IMIDAZOPYRIDINES | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998021209-A1 | NEW IMIDAZOPYRIDINES AND OXAZOLOPYRIDINES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1998-05-22 | — | — | WO | disclosed |
| WO-1997043288-A1 | NOVEL IMIDAZOPYRIDINES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1997-11-20 | — | — | WO | disclosed |
| US-4748172-A | 3-bicyclicpyridinium-methyl cephalosporins | ELI LILLY AND COMPANY (US) | 1988-05-31 | — | — | US | disclosed |
| EP-0266897-A1 | Synthesis of alkylsulfinyl substituted 2-phenylimidazo [4,5-c] pyridines | ELI LILLY AND COMPANY (US) | 1988-05-11 | — | — | EP | disclosed |
| EP-0266897-A1 | Synthesis of alkylsulfinyl substituted 2-phenylimidazo [4,5-c] pyridines | ELI LILLY AND COMPANY (US) | 1988-05-11 | — | — | EP | disclosed |
| US-4740599-A | Synthesis of alkylsulfinyl substituted 2-phenylimidazo(4,5-c)pyridines | ELI LILLY AND COMPANY (US) | 1988-04-26 | — | — | US | disclosed |
| US-4740599-A | Synthesis of alkylsulfinyl substituted 2-phenylimidazo(4,5-c)pyridines | ELI LILLY AND COMPANY (US) | 1988-04-26 | — | — | US | disclosed |
| US-4722929-A | Novel 2-phenyl-imidazoles and pharmaceutical compositions containing same | DR. KARL THOMAE GMBH (DE) | 1988-02-02 | — | — | US | disclosed |
| US-4692443-A | 3-bicyclicpyridinium-methyl cephalosporins | ELI LILLY AND COMPANY (US) | 1987-09-08 | — | — | US | disclosed |
| EP-0149200-A1 | Novel 2-pnenyl-imidazoles, their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1985-07-24 | — | — | EP | disclosed |
| EP-0138552-A2 | Improvements on or relating to 3-bicyclicpyridinium-methyl cephalosporins | ELI LILLY AND COMPANY (US) | 1985-04-24 | — | — | EP | disclosed |
| EP-0093593-A2 | Pyridine compounds | ELI LILLY AND COMPANY (US) | 1983-11-09 | — | — | EP | disclosed |