Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 4/20 | 0.51 |
| ▸ | GABRD | O14764 | 4/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.51 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.51 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.51 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.51 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.51 |
| ▸ | GABRE | P78334 | 4/20 | 0.51 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.51 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.51 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.51 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.51 |
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7125237 | 0.94 | CA12 (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7124757 | 0.92 | GABRP (0.59) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7122361 | 0.89 | CA1 (0.59) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7119204 | 0.86 | CA1 (0.62) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7120677 | 0.82 | CA1 (0.60) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7152314 | 0.82 | CA12 (0.45) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL3091877 | 0.79 | ERAP1 (0.58) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7807865 | 0.79 | CA9 (0.56) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7164554 | 0.78 | CA1 (0.61) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7165990 | 0.76 | ESR1 (0.74) | CA1CA2ESR1ESR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003504327-A | — | — | 2003-02-04 | — | — | JP | claimed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | claimed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | claimed |
| US-6555523-B1 | Such as 3',4'-diacetoxy-5,6,7-trimethoxyflavone or naringin in the treatment HIV, picornavirus, and/or respiratory virus | CASCADE ESTATES LTD. (MU) | 2003-04-29 | — | — | US | disclosed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | disclosed |