Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | KLK1 | P06870 | 2/20 | 0.34 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.34 |
| ▸ | CFD | P00746 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | RAD52 | P43351 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4802588 | 0.95 | MEN1 (0.35) | MEN1KMT2AMAPK14KLKB1ENPP2 | |
| Hydrochloric Acid SCHEMBL4806911 | 0.89 | MEN1 (0.36) | MEN1KMT2AMAPK14ENPP2NPC1 | |
| Trifluoroacetic Acid SCHEMBL4809992 | 0.85 | ENPP2 (0.41) | MEN1KMT2AMAPK14KLKB1ENPP2 | |
| SCHEMBL4812018 | 0.85 | NPC1 (0.35) | MEN1KMT2AMAPK14ENPP2NPC1 | |
| Trifluoroacetic Acid SCHEMBL4809310 | 0.85 | MEN1 (0.35) | MEN1KMT2AMAPK14ENPP2NPC1 | |
| SCHEMBL4812613 | 0.84 | MAPK14 (0.36) | MEN1KMT2AMAPK14KLKB1ENPP2 | |
| SCHEMBL4805867 | 0.84 | MAPT (0.38) | MEN1KMT2AMAPK14NPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL4809932 | 0.84 | MAPK14 (0.35) | MEN1KMT2AMAPK14ENPP2NPC1 | |
| Hydrochloric Acid SCHEMBL4811330 | 0.82 | MAPK14 (0.40) | MEN1KMT2AMAPK14NPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL4807459 | 0.82 | MAPK14 (0.33) | MEN1KMT2AMAPK14ENPP2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294691-A1 | SERINE PROTEASE INHIBITORS | Tularik Limited (GB) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001096305-A1 | SERINE PROTEASE INHIBITORS | TULARIK LIMITED (GB) | 2001-12-20 | — | — | WO | disclosed |