Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 8/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.54 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.54 |
| ▸ | TOP2A | P11388 | 4/20 | 0.53 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7011598 | 0.90 | PDCD1LG2 (0.64) | NISCHPDCD1LG2CD274TOP2ATOP2B | |
| SCHEMBL3058419 | 0.80 | NISCH (0.56) | NISCHGAATSHRPDCD1LG2CD274 | |
| SCHEMBL13327264 | 0.80 | NISCH (0.81) | NISCHGAATSHRTOP2ATOP2B | |
| SCHEMBL20036352 | 0.76 | NISCH (0.51) | NISCHGAATSHRPDCD1LG2CD274 | |
| SCHEMBL20036346 | 0.76 | NISCH (0.51) | NISCHGAATSHRPDCD1LG2CD274 | |
| SCHEMBL5141529 | 0.72 | NISCH (0.80) | NISCHGAATSHRTOP2ATOP2B | |
| SCHEMBL11462790 | 0.72 | NISCH (1.00) | NISCHGAATSHRTOP2ATOP2B | |
| SCHEMBL31249900 | 0.72 | NISCH (0.68) | NISCHGAATSHRTOP2ATOP2B | |
| SCHEMBL2513540 | 0.72 | NISCH (0.68) | NISCHGAATSHRTOP2ATOP2B | |
| SCHEMBL4035056 | 0.72 | NISCH (0.68) | NISCHGAATSHRTOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030100769-A1 | Cyclic amidine compounds | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2003-05-29 | — | — | US | claimed |
| US-20030100769-A1 | Cyclic amidine compounds | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2003-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030100769-A1 | Cyclic amidine compounds | CHRM1, CHRM5, CCKAR | NISCH 1691/4885GAA 4427/4885TSHR 31/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.