Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.72 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.69 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.69 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.64 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.60 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.60 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.60 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.60 |
| ▸ | ALB | P02768 | 1/20 | 0.58 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8864468 | 1.00 | PPARA (0.72) | PPARAHDAC1HDAC2KCNA3FFAR1 | |
| SCHEMBL557510 | 1.00 | PPARA (0.72) | PPARAHDAC1HDAC2KCNA3FFAR1 | |
| SCHEMBL1139655 | 1.00 | PPARA (0.72) | PPARAHDAC1HDAC2KCNA3FFAR1 | |
| SCHEMBL11790866 | 1.00 | PPARA (0.72) | PPARAHDAC1HDAC2KCNA3FFAR1 | |
| SCHEMBL6342300 | 1.00 | PPARA (0.72) | PPARAHDAC1HDAC2KCNA3FFAR1 | |
| SCHEMBL25228768 | 1.00 | PPARA (0.72) | PPARAHDAC1HDAC2KCNA3FFAR1 | |
| SCHEMBL11616532 | 1.00 | PPARA (0.72) | PPARAHDAC1HDAC2KCNA3FFAR1 | |
| SCHEMBL503552 | 1.00 | PPARA (0.72) | PPARAHDAC1HDAC2KCNA3FFAR1 | |
| SCHEMBL1008297 | 1.00 | PPARA (0.72) | PPARAHDAC1HDAC2KCNA3FFAR1 | |
| SCHEMBL1162023 | 0.98 | PPARA (0.74) | PPARAHDAC1HDAC2KCNA3FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220370467-A1 | USING OF A PPAR-DELTA AGONIST IN THE TREATMENT OF KIDNEY DISEASE | WASHINGTON UNIVERSITY | 2022-11-24 | — | — | US | claimed |
| EP-4031124-A1 | USE OF A PPAR-DELTA AGONIST IN THE TREATMENT OF KIDNEY DISEASE | Reneo Pharmaceuticals, Inc. (US) | 2022-07-27 | — | — | EP | claimed |
| CN-114727976-A | Use of PPAR-delta agonists in the treatment of renal disease | 雷内奥制药公司 | 2022-07-08 | — | — | CN | claimed |
| US-20220117972-A1 | USE OF PPAR-DELTA AGONISTS IN THE TREATMENT OF MITOCHONDRIAL MYOPATHY | RENEO PHARMACEUTICALS, INC. | 2022-04-21 | — | — | US | claimed |
| US-20220023306-A1 | USE OF A PPAR-DELTA AGONIST IN THE TREATMENT OF FATTY ACID OXIDATION DISORDERS (FAOD) | RENEO PHARMACEUTICALS, INC. | 2022-01-27 | — | — | US | claimed |
| EP-3927718-A1 | USE OF PPAR-DELTA AGONISTS IN THE TREATMENT OF MITOCHONDRIAL MYOPATHY | Reneo Pharmaceuticals, Inc. (US) | 2021-12-29 | — | — | EP | claimed |
| EP-3920903-A1 | USE OF A PPAR-DELTA AGONIST IN THE TREATMENT OF FATTY ACID OXIDATION DISORDERS (FAOD) | Reneo Pharmaceuticals, Inc. (US) | 2021-12-15 | — | — | EP | claimed |
| CN-113747891-A | Use of PPAR delta agonists in the treatment of Fatty Acid Oxidation Disorders (FAOD) | 雷内奥制药公司 | 2021-12-03 | — | — | CN | claimed |
| CN-113710683-A | Use of PPAR-delta agonists in the treatment of mitochondrial myopathy | 雷内奥制药公司 | 2021-11-26 | — | — | CN | claimed |
| WO-2021055725-A1 | USE OF A PPAR-DELTA AGONIST IN THE TREATMENT OF KIDNEY DISEASE | RENEO PHARMACEUTICALS, INC. (US) | 2021-03-25 | — | — | WO | claimed |
| WO-2020163240-A1 | USE OF A PPAR-DELTA AGONIST IN THE TREATMENT OF FATTY ACID OXIDATION DISORDERS (FAOD) | RENEO PHARMACEUTICALS, INC. (US) | 2020-08-13 | — | — | WO | claimed |
| US-11931365-B2 | Use of PPAR-delta agonists in the treatment of disease | RENEO PHARMACEUTICALS, INC. (US) | 2024-03-19 | — | — | US | disclosed |
| US-20240016809-A1 | USE OF PPAR-DELTA AGONISTS IN THE TREATMENT OF DISEASE | RENEO PHARMACEUTICALS, INC. | 2024-01-18 | — | — | US | disclosed |
| EP-4294878-A1 | COATING COMPOSITION COMPRISING A PIGMENT PASTE COMPRISING AN ORGANIC PIGMENT AND AN ARYL-MODIFIED BRANCHED REACTION PRODUCT | BASF Coatings GmbH (DE) | 2023-12-27 | — | — | EP | disclosed |
| WO-2023147309-A1 | USE OF PPAR-DELTA AGONISTS IN THE TREATMENT OF DISEASE | RENEO PHARMACEUTICALS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| EP-1113033-A2 | Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same | CANON KABUSHIKI KAISHA (JP) | 2001-07-04 | — | — | EP | disclosed |
| EP-0487343-B1 | Process for preparing a lithographic plate | FUJI PHOTO FILM CO LTD (JP) | 1999-04-28 | — | — | EP | disclosed |
| EP-0487343-A1 | Process for preparing a lithographic plate | Fuji Photo Film Co., Ltd. (JP) | 1992-05-27 | — | — | EP | disclosed |
| EP-0128598-B1 | THERMOPLASTIC MOULDING COMPOSITION | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1987-05-13 | — | — | EP | disclosed |
| US-4508541-A | DETERGENTS | TEXACO INC. (US) | 1985-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220370467-A1 | USING OF A PPAR-DELTA AGONIST IN THE TREATMENT OF KIDNEY DISEASE | PPARG, PPARA, PPARD | PPARA 2/4885HDAC1 1595/4885HDAC2 2519/4885 |
| US-11931365-B2 | Use of PPAR-delta agonists in the treatment of disease | PPARG, PPARD, PPARA | PPARA 3/4885HDAC1 721/4885HDAC2 1013/4885 |
| US-20220117972-A1 | USE OF PPAR-DELTA AGONISTS IN THE TREATMENT OF MITOCHONDRIAL MYOPATHY | PPARD, PPARA, MTPN | PPARA 2/4885HDAC1 2295/4885HDAC2 2749/4885 |
| US-20240016809-A1 | USE OF PPAR-DELTA AGONISTS IN THE TREATMENT OF DISEASE | PPARG, PPARD, PPARA | PPARA 3/4885HDAC1 721/4885HDAC2 1013/4885 |
| US-20220023306-A1 | USE OF A PPAR-DELTA AGONIST IN THE TREATMENT OF FATTY ACID OXIDATION DISORDERS (FAOD) | PPARD, ACOX1, CPT1A | PPARA 8/4885HDAC1 1881/4885HDAC2 1743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.