Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.72 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.69 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.69 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.64 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.60 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.60 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.60 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.60 |
| ▸ | ALB | P02768 | 1/20 | 0.58 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL712775 | 1.00 | PPARA (0.72) | PPARAHDAC1HDAC2KCNA3FFAR1 | |
| SCHEMBL6342300 | 1.00 | PPARA (0.72) | PPARAHDAC1HDAC2KCNA3FFAR1 | |
| SCHEMBL1139655 | 1.00 | PPARA (0.72) | PPARAHDAC1HDAC2KCNA3FFAR1 | |
| SCHEMBL503552 | 1.00 | PPARA (0.72) | PPARAHDAC1HDAC2KCNA3FFAR1 | |
| SCHEMBL11790866 | 1.00 | PPARA (0.72) | PPARAHDAC1HDAC2KCNA3FFAR1 | |
| SCHEMBL25228768 | 1.00 | PPARA (0.72) | PPARAHDAC1HDAC2KCNA3FFAR1 | |
| SCHEMBL557510 | 1.00 | PPARA (0.72) | PPARAHDAC1HDAC2KCNA3FFAR1 | |
| SCHEMBL11616532 | 1.00 | PPARA (0.72) | PPARAHDAC1HDAC2KCNA3FFAR1 | |
| SCHEMBL1008297 | 1.00 | PPARA (0.72) | PPARAHDAC1HDAC2KCNA3FFAR1 | |
| SCHEMBL1162023 | 0.98 | PPARA (0.74) | PPARAHDAC1HDAC2KCNA3FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525479-B1 | Spicamycin derivatives and the use thereof | KIRIN BREWERY (JP) | 1997-11-05 | — | — | EP | disclosed |
| US-5631238-A | ANTICARCINOGENIC AGENTS | KIRIN BEER KABUSHIKI KAISHA (JP) | 1997-05-20 | — | — | US | disclosed |
| US-5461036-A | Treating colon, gastric, esophageal cancer | KIRIN BEER KABUSHIKI KAISHA (JP) | 1995-10-24 | — | — | US | disclosed |
| EP-0525479-A1 | Spicamycin derivatives and the use thereof | KIRIN BEER KABUSHIKI KAISHA (JP) | 1993-02-03 | — | — | EP | disclosed |
| US-4097665-A | Diacylnucleosides and process for preparing the same | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) | 1978-06-27 | — | — | US | disclosed |