SCHEMBL7127795

SCHEMBL7127795

COCCNC(=O)c1cc(S(N)(=O)=O)c(Cl)cc1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 19/20 1.00
▸ CA2 P00918 19/20 1.00
▸ CA9 Q16790 18/20 1.00
▸ CA12 O43570 18/20 1.00
▸ CA3 P07451 17/20 1.00
▸ CA6 P23280 17/20 1.00
▸ CA5A P35218 17/20 1.00
▸ CA7 P43166 17/20 1.00
▸ CA13 Q8N1Q1 17/20 1.00
▸ CA14 Q9ULX7 17/20 1.00
▸ CA5B Q9Y2D0 17/20 1.00
▸ CA4 P22748 15/20 1.00
▸ SMN1; SMN2 Q16637 1/20 0.70
▸ HPGD P15428 1/20 0.54
▸ CISD1 Q9NZ45 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18425536 0.85 CA1 (1.00) CA1CA2CA9CA12CA3
SCHEMBL18423865 0.85 CA1 (1.00) CA1CA2CA9CA12CA3
SCHEMBL18425907 0.84 CA1 (1.00) CA1CA2CA9CA12CA3
SCHEMBL18423758 0.84 CA1 (1.00) CA1CA2CA9CA12CA3
SCHEMBL18424450 0.82 CA1 (1.00) CA1CA2CA9CA12CA3
SCHEMBL18425354 0.82 CA1 (1.00) CA1CA2CA9CA12CA3
SCHEMBL18425070 0.81 CA12 (1.00) CA1CA2CA9CA12CA3
SCHEMBL18424947 0.81 CA1 (1.00) CA1CA2CA9CA12CA3
SCHEMBL18424707 0.81 CA1 (0.67) CA1CA2CA9CA12CA3
SCHEMBL31670540 0.80 CA1 (0.70) CA1CA2CA9CA12CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3328833-B1 SELECTIVE INHIBITORS OF CARBONIC ANHYDRASE UNIV VILNIUS (LT) 2025-08-06 — — EP disclosed
US-11312682-B2 Selective inhibitors of carbonic anhydrase VILNIUS UNIVERSITY (LT) 2022-04-26 — — US disclosed
US-20180222856-A1 SELECTIVE INHIBITORS OF CARBONIC ANHYDRASE VILNIUS UNIVERSITY (LT) 2018-08-09 — — US disclosed
EP-3328833-A1 SELECTIVE INHIBITORS OF CARBONIC ANHYDRASE Vilnius University (LT) 2018-06-06 — — EP disclosed
WO-2017017505-A1 SELECTIVE INHIBITORS OF CARBONIC ANHYDRASE VILNIUS UNIVERSITY (LT) 2017-02-02 — — WO disclosed
EP-1019368-B1 ACYLSULFAMOYL BENZOIC ACID AMIDES, PLANT PROTECTION AGENTS CONTAINING SAID ACYLSULFAMOYL BENZOIC ACID AMIDES, AND METHOD FOR PRODUCING THE SAME BAYER CROPSCIENCE GMBH (DE) 2003-03-05 — — EP disclosed
US-6251827-B1 MIXTURE OF PLANT SAFENING AGENT AND ONE OR MORE PESTICIDES HOECHST SCHERING AGREVO GMBH (DE) 2001-06-26 — — US disclosed
CN-1272106-A Acylsulfamoylbenzamides, crop protection compositions containing them and processes for their preparation HOECHST SCHERING AGREVO GMBH (DE) 2000-11-01 — — CN disclosed
EP-1019368-A1 ACYLSULFAMOYL BENZOIC ACID AMIDES, PLANT PROTECTION AGENTS CONTAINING SAID ACYLSULFAMOYL BENZOIC ACID AMIDES, AND METHOD FOR PRODUCING THE SAME Aventis CropScience GmbH (DE) 2000-07-19 — — EP disclosed
WO-1999016744-A1 ACYLSULFAMOYL BENZOIC ACID AMIDES, PLANT PROTECTION AGENTS CONTAINING SAID ACYLSULFAMOYL BENZOIC ACID AMIDES, AND METHOD FOR PRODUCING THE SAME AVENTIS CROPSCIENCE GMBH (DE) 1999-04-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11312682-B2 Selective inhibitors of carbonic anhydrase CA2, CA9, CA7 CA1 6/4885CA2 1/4885CA9 2/4885
US-20180222856-A1 SELECTIVE INHIBITORS OF CARBONIC ANHYDRASE CA9, CA2, CA7 CA1 6/4885CA2 2/4885CA9 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback