SCHEMBL7127932

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8093512	0.83	EGFR (0.53)	ERBB2EGFR
	SCHEMBL7127206	0.81	EGFR (0.50)	ERBB2FYNSRCEGFR
	SCHEMBL7120503	0.79	EGFR (0.50)	ERBB2FYNSRCEGFR
	SCHEMBL7128226	0.79	EGFR (0.51)	ERBB2FYNSRCEGFR
	SCHEMBL8089915	0.79	ERBB2 (0.53)	ERBB2ALDH1A1CYP1A2CYP2D6CYP2C19
	SCHEMBL7119065	0.79	EGFR (0.54)	ERBB2FYNSRCEGFR
	SCHEMBL7119474	0.77	EGFR (0.51)	ERBB2ADORA2AEGFR
	SCHEMBL7126329	0.77	EGFR (0.45)	ERBB2EGFR
	SCHEMBL7129916	0.77	EGFR (0.39)	FYNSRCALDH1A1EGFR
	SCHEMBL7122220	0.77	EGFR (0.49)	ERBB2EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.