Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089915 | 0.88 | ERBB2 (0.53) | EGFRERBB2 | |
| SCHEMBL7127932 | 0.83 | ERBB2 (0.44) | EGFRERBB2 | |
| SCHEMBL7120503 | 0.81 | EGFR (0.50) | EGFRERBB2 | |
| SCHEMBL7127206 | 0.81 | EGFR (0.50) | EGFRERBB2 | |
| SCHEMBL7119065 | 0.79 | EGFR (0.54) | EGFRERBB2 | |
| SCHEMBL7128226 | 0.77 | EGFR (0.51) | EGFRERBB2 | |
| SCHEMBL7120078 | 0.77 | EGFR (0.50) | EGFRERBB2 | |
| SCHEMBL7119474 | 0.77 | EGFR (0.51) | EGFRERBB2 | |
| SCHEMBL7126329 | 0.77 | EGFR (0.45) | EGFRERBB2 | |
| SCHEMBL7122220 | 0.76 | EGFR (0.49) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153617-A | Irreversible bicyclic inhibitors of tyrosine kinases | WARNER-LAMBERT COMPANY (US) | 2000-11-28 | — | — | US | claimed |
| WO-1999006396-A1 | IRREVERSIBLE BICYCLIC INHIBITORS OF TYROSINE KINASES | WARNER-LAMBERT COMPANY (US) | 1999-02-11 | — | — | WO | claimed |
| US-6153617-A | Irreversible bicyclic inhibitors of tyrosine kinases | WARNER-LAMBERT COMPANY (US) | 2000-11-28 | — | — | US | disclosed |
| WO-1999006396-A1 | IRREVERSIBLE BICYCLIC INHIBITORS OF TYROSINE KINASES | WARNER-LAMBERT COMPANY (US) | 1999-02-11 | — | — | WO | disclosed |