Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 3/20 | 0.65 |
| ▸ | KIF11 | P52732 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | ACHE | P22303 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.55 |
| ▸ | PTGES | O14684 | 1/20 | 0.55 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | STAT1 | P42224 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17364440 | 0.88 | TSHR (0.70) | HPGDRAB9AKMT2AMEN1MAPT | |
| SCHEMBL20049529 | 0.88 | HPGD (0.78) | HPGDALOX12L3MBTL1RAB9AKIF11 | |
| SCHEMBL9186456 | 0.87 | RAB9A (0.61) | HPGDALOX12L3MBTL1RAB9AKIF11 | |
| SCHEMBL11029782 | 0.84 | HPGD (0.61) | HPGDALOX12L3MBTL1RAB9AKIF11 | |
| SCHEMBL9243623 | 0.83 | KMT2A (0.59) | HPGDALOX12L3MBTL1RAB9AKIF11 | |
| SCHEMBL416650 | 0.82 | NPSR1 (0.68) | HPGDRAB9AKMT2AMEN1MAPT | |
| SCHEMBL4626757 | 0.82 | HSD17B10 (0.75) | HPGDALOX12L3MBTL1RAB9AKIF11 | |
| SCHEMBL30145137 | 0.82 | NPSR1 (0.86) | HPGDALOX12L3MBTL1KMT2AMEN1 | |
| SCHEMBL1922070 | 0.82 | NPSR1 (0.86) | HPGDALOX12L3MBTL1KMT2AMEN1 | |
| SCHEMBL10523964 | 0.82 | NPSR1 (0.86) | HPGDALOX12L3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111732516-B | A kind ofNProcess for preparing (E) -aryl-substituted heterocyclic compounds | 南昌大学 | 2021-01-05 | — | — | CN | disclosed |
| CN-111732516-A | A kind ofNProcess for preparing (E) -aryl-substituted heterocyclic compounds | 南昌大学 | 2020-10-02 | — | — | CN | disclosed |
| US-20030162795-A1 | Thienopyrimidine and thienopyridine derivatives useful as anticancer agents | PFIZER INC. | 2003-08-28 | — | — | US | disclosed |
| US-6492383-B1 | Thienopyrimidine and thienopyridine derivatives useful as anticancer agents | PFIZER INC. | 2002-12-10 | — | — | US | disclosed |
| EP-1028964-A1 | THIENOPYRIMIDINE AND THIENOPYRIDINE DERIVATIVES USEFUL AS ANTICANCER AGENTS | Pfizer Products Inc. (US) | 2000-08-23 | — | — | EP | disclosed |
| WO-1999024440-A1 | THIENOPYRIMIDINE AND THIENOPYRIDINE DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER PRODUCTS INC. (US) | 1999-05-20 | — | — | WO | disclosed |
| US-4296037-A | 4,5-Dihydro-3,3-diphenyl-4-hydrocarbylaminomethylfuran-2(3H) ones | A. H. ROBINS COMPANY, INCORPORATED (US) | 1981-10-20 | — | — | US | disclosed |
| US-4296037-A | 4,5-Dihydro-3,3-diphenyl-4-hydrocarbylaminomethylfuran-2(3H) ones | A. H. ROBINS COMPANY, INCORPORATED (US) | 1981-10-20 | — | — | US | disclosed |
| EP-0011790-B1 | PROCESS FOR THE PREPARATION OF NITRODIPHENYL AMINE DERIVATIVES | BAYER AG (DE) | 1981-07-15 | — | — | EP | disclosed |
| US-4238407-A | Process for the preparation of nitro diphenyl amine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-09 | — | — | US | disclosed |
| EP-0011790-A1 | Process for the preparation of nitrodiphenyl amine derivatives | BAYER AG (DE) | 1980-06-11 | — | — | EP | disclosed |
| US-4144245-A | 4-Hydroxymethyl-2-pyrrolidinones | A. H. ROBINS COMPANY, INC. (US) | 1979-03-13 | — | — | US | disclosed |
| US-4144245-A | 4-Hydroxymethyl-2-pyrrolidinones | A. H. ROBINS COMPANY, INC. (US) | 1979-03-13 | — | — | US | disclosed |
| US-4122118-A | Copper-N-methylpyrrolidone catalyst useful in the production of nitrodiphenyl amines | BAYER AKTIENGESELLSCHAFT (DE) | 1978-10-24 | — | — | US | disclosed |
| US-4119637-A | 4-Hydroxymethyl-2-pyrrolidinones | A. H. ROBINS COMPANY, INC. (US) | 1978-10-10 | — | — | US | disclosed |
| US-4119637-A | 4-Hydroxymethyl-2-pyrrolidinones | A. H. ROBINS COMPANY, INC. (US) | 1978-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162795-A1 | Thienopyrimidine and thienopyridine derivatives useful as anticancer agents | TYMP, DPYD, HPRT1 | HPGD 162/4885ALOX12 2654/4885L3MBTL1 948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.