Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.65 |
| ▸ | MGAM | O43451 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SI | P14410 | 1/20 | 0.52 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL134985 | 0.92 | — | — | |
| Methyl Alcohol SCHEMBL811559 | 0.90 | TSHR (0.72) | TSHRMGAMGAASIMGAM2 | |
| Dimethyl Succinate SCHEMBL7895030 | 0.89 | TSHR (0.81) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL16972751 | 0.88 | TSHR (0.62) | TSHRMGAMGAASIMGAM2 | |
| Iodomethane SCHEMBL8981694 | 0.87 | TSHR (0.68) | TSHRMGAMGAASIMGAM2 | |
| Hexane SCHEMBL4632599 | 0.86 | TSHR (0.59) | TSHRMGAMGAASIMGAM2 | |
| Ether SCHEMBL12981250 | 0.86 | TSHR (0.59) | TSHRMGAMGAASIMGAM2 | |
| Dimethyl Succinate SCHEMBL7902252 | 0.84 | TSHR (0.72) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL17711585 | 0.83 | TSHR (0.50) | TSHRMGAMGAASIMGAM2 | |
| Glycerin SCHEMBL28672730 | 0.82 | TSHR (0.54) | TSHRMGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6660074-B1 | Emission coating comprising iron oxide and/or cobalt oxide, carbonate of metal selected from barium, strontium and calcium, optionally peroxide of metal selected from barium, strontium and calcium; compatible for metal electrode surfaces | EGL COMPANY, INC. | 2003-12-09 | — | — | US | disclosed |