Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.72 |
| ▸ | MGAM | O43451 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | SI | P14410 | 1/20 | 0.57 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL134985 | 0.86 | — | — | |
| Dimethyl Succinate SCHEMBL28054469 | 0.85 | TSHR (1.00) | TSHRMGAMGAASIMGAM2 | |
| Dimethyl Succinate SCHEMBL10213 | 0.85 | TSHR (1.00) | TSHRMGAMGAASIMGAM2 | |
| Alcohol SCHEMBL7128451 | 0.84 | TSHR (0.65) | TSHRMGAMGAASIMGAM2 | |
| Methyl Alcohol SCHEMBL811559 | 0.83 | TSHR (0.72) | TSHRMGAMGAASIMGAM2 | |
| Dimethyl Succinate SCHEMBL28198016 | 0.83 | TSHR (0.72) | TSHRMGAMGAASIMGAM2 | |
| Dimethyl Succinate SCHEMBL7895030 | 0.82 | TSHR (0.81) | TSHRMGAMGAASIMGAM2 | |
| Dimethyl Succinate SCHEMBL28180608 | 0.82 | TSHR (0.81) | TSHRMGAMGAASIMGAM2 | |
| Dimethyl Succinate SCHEMBL28197319 | 0.82 | TSHR (0.81) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL7126720 | 0.82 | TSHR (0.81) | TSHRMGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6190646-B1 | AS BIODEGRADATION ACCELERATOR OF HYDROPHOBIC POLLUTANTS SUCH AS HYDROCARBONS | ELF AQUITAINE (FR) | 2001-02-20 | — | — | US | claimed |