Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7123982 | 1.00 | ELANE (0.43) | ELANETAS1R3TAS1R1MAPTLMNA | |
| SCHEMBL7123976 | 1.00 | ELANE (0.43) | ELANETAS1R3TAS1R1MAPTLMNA | |
| Hydrochloric Acid SCHEMBL7125040 | 0.78 | ELANE (0.51) | ELANETAS1R3TAS1R1MAPTLMNA | |
| SCHEMBL7117247 | 0.75 | ELANE (0.33) | ELANE | |
| SCHEMBL7117896 | 0.75 | ELANE (0.33) | ELANE | |
| SCHEMBL7117242 | 0.75 | ELANE (0.33) | ELANE | |
| SCHEMBL7158905 | 0.72 | ELANE (0.42) | ELANEMAPTLMNAHSP90AA1HTT | |
| SCHEMBL7117137 | 0.70 | ELANE (0.40) | ELANEMAPTALDH1A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7112519 | 0.69 | ELANE (0.40) | ELANEMAPTHTTALDH1A1NPC1 | |
| Hydrochloric Acid SCHEMBL8494600 | 0.69 | ELANE (0.40) | ELANEMAPTHTTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030130326-A1 | 1,3,4-oxadiazole derivatives and process for producing the same | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-07-10 | — | — | US | claimed |
| EP-1253144-A1 | 1,3,4-OXADIAZOLE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-10-30 | — | — | EP | claimed |
| US-20030130326-A1 | 1,3,4-oxadiazole derivatives and process for producing the same | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-07-10 | — | — | US | disclosed |
| EP-1253144-A1 | 1,3,4-OXADIAZOLE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-10-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130326-A1 | 1,3,4-oxadiazole derivatives and process for producing the same | SERPINB1, CELA1, ELANE | ELANE 3/4885TAS1R3 2035/4885TAS1R1 1798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.