Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7818468 | 0.80 | ALOX5 (0.40) | ALOX5GAA | |
| SCHEMBL3636655 | 0.79 | ALOX5 (0.43) | ALOX5GAANPSR1 | |
| SCHEMBL9933935 | 0.79 | ALOX5 (0.43) | ALOX5GAANPSR1 | |
| SCHEMBL9933931 | 0.77 | ALOX5 (0.45) | ALOX5GAANPSR1 | |
| SCHEMBL3638132 | 0.76 | ALOX5 (0.45) | ALOX5GAANPSR1 | |
| SCHEMBL3805431 | 0.76 | ALOX5 (0.41) | ALOX5GAANPSR1 | |
| SCHEMBL3638693 | 0.73 | ALOX5 (0.42) | ALOX5GAANPSR1 | |
| SCHEMBL3637187 | 0.69 | ALOX5 (0.48) | ALOX5GAANPSR1 | |
| SCHEMBL9934059 | 0.65 | ALOX5 (0.48) | ALOX5GAANPSR1 | |
| SCHEMBL22053502 | 0.65 | ALOX5 (0.43) | ALOX5GAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762193-B1 | Method of treating hair loss | SANDERS JR RICHARD J (US) | 2004-07-13 | — | — | US | disclosed |
| US-6440994-B1 | Method of treating acne | SANDERS JR RICHARD J (US) | 2002-08-27 | — | — | US | disclosed |
| US-5486515-A | 2-fluoroalkyl-1,4-benzoxaxines as potassium channel mediators | ZENECA LIMITED (GB) | 1996-01-23 | — | — | US | disclosed |