Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | PPARG | P37231 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | PPARA | Q07869 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | RORC | P51449 | 9/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7124282 | 0.80 | RORC (0.62) | SMN1; SMN2CYP3A4MAPK1PPARGALOX15 | |
| SCHEMBL7123389 | 0.80 | RORC (0.61) | SMN1; SMN2CYP3A4MAPK1PPARGALOX15 | |
| SCHEMBL7129183 | 0.79 | SMN1; SMN2 (0.69) | SMN1; SMN2CYP3A4MAPK1PPARGALOX15 | |
| SCHEMBL422653 | 0.79 | GAA (0.64) | SMN1; SMN2CYP3A4MAPK1PPARGALOX15 | |
| SCHEMBL15547417 | 0.78 | SMN1; SMN2 (0.68) | SMN1; SMN2CYP3A4MAPK1PPARGALOX15 | |
| SCHEMBL27589554 | 0.77 | RORC (0.62) | SMN1; SMN2CYP3A4MAPK1PPARGALOX15 | |
| SCHEMBL7121694 | 0.76 | RORC (0.69) | SMN1; SMN2CYP3A4MAPK1PPARGALOX15 | |
| SCHEMBL18146933 | 0.76 | RORC (0.61) | SMN1; SMN2CYP3A4MAPK1PPARGALOX15 | |
| SCHEMBL7127143 | 0.75 | SMN1; SMN2 (0.66) | SMN1; SMN2CYP3A4MAPK1PPARGALOX15 | |
| SCHEMBL7130573 | 0.75 | MEN1 (0.71) | SMN1; SMN2CYP3A4MAPK1PPARGALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1440383-A | PPAR gamma modulators | SANKYO CO (JP) | 2003-09-03 | — | — | CN | disclosed |
| EP-1277729-A1 | PPAR (GAMMA) MODULATORS | Sankyo Company, Limited (JP) | 2003-01-22 | — | — | EP | disclosed |