Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7077027 | 0.92 | KMT2A (0.43) | F10MAP4K4GRM5KCNH2SCN9A | |
| SCHEMBL7130914 | 0.92 | KMT2A (0.43) | F10MAP4K4GRM5KCNH2SCN9A | |
| SCHEMBL6579304 | 0.86 | MAP4K4 (0.53) | F10MAP4K4GRM5 | |
| SCHEMBL7070093 | 0.86 | AR (0.41) | F10KDM4E | |
| SCHEMBL7071621 | 0.84 | GRM5 (0.43) | MAP4K4GRM5KCNH2SCN9ASCN5A | |
| SCHEMBL7074801 | 0.79 | KCNH2 (0.37) | GRM5HPGDSSMN1; SMN2KCNH2KDM4E | |
| SCHEMBL7071599 | 0.78 | MAP4K4 (0.45) | F10MAP4K4GRM5 | |
| SCHEMBL7075065 | 0.77 | EPAS1 (0.39) | — | |
| SCHEMBL7074411 | 0.75 | MEN1 (0.50) | MAP4K4LMNA | |
| SCHEMBL7074436 | 0.75 | AR (0.47) | F10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030181334-A1 | Herbicidal method | BAYER CROPSCIENCE LIMITED (GB) | 2003-09-25 | — | — | US | disclosed |
| US-6596741-B2 | Compounds of formula I exhibit activity as serotonin, norepinephrine, and dopamine reuptake inhibitors and can be used in the treatment of central nervous system and other disorders. | PFIZER INC | 2003-07-22 | — | — | US | disclosed |
| WO-2003051119-A1 | NEW HERBICIDAL COMPOUNDS AND METHOD | BAYER CROPSCIENCE LIMITED (GB) | 2003-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030181334-A1 | Herbicidal method | DDT, HAAO, CYP4X1 | F10 4503/4885MAP4K4 4418/4885GRM5 792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.