SCHEMBL7074411

SCHEMBL7074411

N#Cc1cc(C#N)cc(Oc2cccc(Oc3ncccn3)c2)c1

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
APAF1 O14727 1/20 0.44
RAB9A P51151 2/20 0.42
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
HTT P42858 1/20 0.42
CYP19A1 P11511 1/20 0.41
TLR4 O00206 1/20 0.41
TLR2 O60603 1/20 0.41
CLK4 Q9HAZ1 1/20 0.41
CKS1B P61024 1/20 0.41
SKP2 Q13309 1/20 0.41
LMNA P02545 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
FFAR1 O14842 1/20 0.39
FFAR4 Q5NUL3 1/20 0.39
MAP4K4 O95819 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8605442 0.90 MEN1 (0.53) MEN1KMT2AAPAF1RAB9AGAA
SCHEMBL7070749 0.86 SMN1; SMN2 (0.50) MEN1KMT2ARAB9AGAAMAPT
SCHEMBL7069974 0.82 PDE4A (0.50) MEN1KMT2AGAAMAPTCYP19A1
SCHEMBL7072557 0.82 PDE4A (0.50) MEN1KMT2AGAAMAPTCYP19A1
SCHEMBL8457829 0.81 RAB9A (0.51) MEN1KMT2ARAB9A
SCHEMBL7074202 0.81 SYK (0.44) RAB9ACKS1BSKP2FFAR1FFAR4
SCHEMBL7070717 0.80 MEN1 (0.50) MEN1KMT2ARAB9AGAAMAPT
SCHEMBL7074089 0.80 SMN1; SMN2 (0.41) MEN1KMT2AHTTCKS1BSKP2
SCHEMBL7073983 0.79 CYP19A1 (0.54) MEN1KMT2ARAB9AGAAMAPT
SCHEMBL8459630 0.79 KCNH2 (0.40) MEN1KMT2AAPAF1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030181334-A1 Herbicidal method BAYER CROPSCIENCE LIMITED (GB) 2003-09-25 US disclosed
WO-2003051119-A1 NEW HERBICIDAL COMPOUNDS AND METHOD BAYER CROPSCIENCE LIMITED (GB) 2003-06-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030181334-A1 Herbicidal method DDT, HAAO, CYP4X1 MEN1 4787/4885KMT2A 1086/4885APAF1 2817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.