SCHEMBL7129664

SCHEMBL7129664

Cc1cc2scnc2c2ccccc12.c1ccc2c(c1)ccc1ncsc12

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
HSD17B10 Q99714 2/20 0.35
MAOA P21397 1/20 0.35
TGFBR1 P36897 1/20 0.34
CCR1 P32246 1/20 0.33
CCR8 P51685 1/20 0.33
PRKD1 Q15139 1/20 0.33
CYP1A2 P05177 4/20 0.33
CYP3A4 P08684 1/20 0.33
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
CYP2A6 P11509 3/20 0.32
TSHR P16473 1/20 0.32
NTRK1 P04629 1/20 0.32
NTRK2 Q16620 1/20 0.32
MAPT P10636 2/20 0.32
HPGD P15428 2/20 0.32
PDE10A Q9Y233 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
BACE1 P56817 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11565679 0.84 ALDH1A1 (0.41) ALDH1A1HSD17B10MAOATGFBR1CYP3A4
SCHEMBL5080792 0.83 ALDH1A1 (0.39) ALDH1A1HSD17B10TGFBR1CCR1CCR8
SCHEMBL29871387 0.80 CYP3A4 (0.47) ALDH1A1HSD17B10CYP3A4KMT2AMEN1
SCHEMBL2852558 0.80 CYP3A4 (0.47) ALDH1A1HSD17B10CYP3A4KMT2AMEN1
SCHEMBL9173990 0.74 CYP1A2 (0.40) ALDH1A1HSD17B10CCR1CCR8CYP1A2
SCHEMBL28846419 0.73 HPRT1 (0.50) ALDH1A1HSD17B10CYP3A4KMT2AMEN1
SCHEMBL4154752 0.73 HPRT1 (0.50) ALDH1A1HSD17B10CYP3A4KMT2AMEN1
SCHEMBL9297639 0.72 KMT2A (0.37) ALDH1A1KMT2AMEN1MAPTHPGD
SCHEMBL272930 0.70 ALDH1A1 (0.42) ALDH1A1HSD17B10CYP3A4KMT2AMEN1
SCHEMBL10461143 0.70 ALDH1A1 (0.41) ALDH1A1HSD17B10MAOATGFBR1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030215760-A1 Silver halide photographic emulsion and silver halide photographic material containing said silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. 2003-11-20 US disclosed
US-6387610-B1 SILVER HALIDE EMULSION SPECTRA SENSITIZED FUJI PHOTO FILM CO., LTD. (JP) 2002-05-14 US disclosed