Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | TDO2 | P48775 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9240130 | 0.89 | ALDH1A1 (0.47) | IDO1TDO2HDAC3HDAC4HDAC1 | |
| SCHEMBL6204475 | 0.81 | IDO1 (0.44) | IDO1TDO2HDAC3HDAC4HDAC1 | |
| SCHEMBL1046731 | 0.79 | IDO1 (0.42) | IDO1TDO2HDAC3HDAC4HDAC1 | |
| SCHEMBL4427290 | 0.78 | IDO1 (0.46) | IDO1TDO2HDAC3HDAC4HDAC1 | |
| SCHEMBL2732165 | 0.78 | IDO1 (0.46) | IDO1TDO2HDAC3HDAC4HDAC1 | |
| SCHEMBL2092079 | 0.76 | TSHR (0.42) | IDO1TDO2ALDH1A1LMNA | |
| SCHEMBL2489611 | 0.76 | IDO1 (0.50) | IDO1TDO2HDAC3HDAC4HDAC1 | |
| SCHEMBL18242519 | 0.75 | AOC3 (0.39) | IDO1TDO2HDAC3HDAC4HDAC1 | |
| SCHEMBL4048358 | 0.73 | IDO1 (0.48) | IDO1TDO2HDAC3HDAC4HDAC1 | |
| SCHEMBL168223 | 0.73 | IDO1 (0.38) | IDO1TDO2HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686635-A1 | Pyridylthiazolidinecarboxylic acid amide derivatives, their preparation and their therapeutic uses | Sankyo Company Limited (JP) | 1995-12-13 | — | — | EP | claimed |
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | claimed |
| EP-0549364-A1 | Pyridylthiazolidinecarboxylic acid amide derivatives, their preparation and their therapeutic uses | Sankyo Company Limited (JP) | 1993-06-30 | — | — | EP | claimed |
| US-6670375-B2 | Particularly, 8-aza-, 8-carbo- and 8-oxo- tropanes having 6-or 7-substituents; preferred are the dopamine transporter, the serotonin transporter and the norepinephrine transporter. | ORGANIX, INC. | 2003-12-30 | — | — | US | disclosed |
| EP-0686635-A1 | Pyridylthiazolidinecarboxylic acid amide derivatives, their preparation and their therapeutic uses | Sankyo Company Limited (JP) | 1995-12-13 | — | — | EP | disclosed |
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0549364-A1 | Pyridylthiazolidinecarboxylic acid amide derivatives, their preparation and their therapeutic uses | Sankyo Company Limited (JP) | 1993-06-30 | — | — | EP | disclosed |