Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | MMP9 | P14780 | 2/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1760416 | 0.72 | CA2 (0.44) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL20808190 | 0.72 | CA2 (0.41) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL4524413 | 0.72 | CA2 (0.48) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL25067844 | 0.72 | CA2 (0.42) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL28523519 | 0.72 | CA2 (0.38) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL20746489 | 0.71 | CA2 (0.44) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL20746467 | 0.71 | CA2 (0.44) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL6245418 | 0.71 | CA2 (0.44) | CA2ALDH1A1NPSR1TMEM97SIGMAR1 | |
| SCHEMBL936957 | 0.70 | — | — | |
| SCHEMBL935836 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0966414-B1 | TRIARYLMETHYL FREE RADICALS AS IMAGE ENHANCING AGENTS | AMERSHAM HEALTH AS (NO) | 2003-06-04 | — | — | EP | disclosed |
| US-6063360-A | USEFUL AS CONTRAST AGENT FOR OVERHAUSER MAGNETIC RESONACE IMAGING | NYCOMED IMAGING A/S (NO) | 2000-05-16 | — | — | US | disclosed |