Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PEPD | P12955 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3097658 | 1.00 | PEPD (0.43) | PEPDMEN1BLMKMT2AACE | |
| SCHEMBL2034245 | 0.84 | — | — | |
| SCHEMBL5897097 | 0.84 | — | — | |
| SCHEMBL2692497 | 0.84 | — | — | |
| SCHEMBL3228170 | 0.84 | — | — | |
| SCHEMBL25347129 | 0.84 | GABRR1 (0.43) | MEN1KMT2AGABRR1 | |
| SCHEMBL2693338 | 0.84 | — | — | |
| SCHEMBL6559471 | 0.84 | — | — | |
| SCHEMBL3228177 | 0.84 | — | — | |
| SCHEMBL5897084 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6670168-B1 | Cell comprises a modified rapamycin polyketide synthase (PKS) gene cluster with an acyltransferase (AT) domain in extender module 10 having malonyl CoA specificity. | KOSAN BIOSCIENCE, INC. | 2003-12-30 | — | — | US | disclosed |