SCHEMBL7130277

SCHEMBL7130277

C=C(C)C(=O)OCC(N=C=O)N=C=O

nearest known ligand 0.55

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.55
THRB P10828 1/20 0.39
ALDH1A1 P00352 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1132033 0.85 TSHR (0.55) TSHRTHRBALDH1A1
SCHEMBL31059955 0.84 TSHR (0.53) TSHRTHRBALDH1A1
SCHEMBL28471483 0.84 TSHR (0.53) TSHRTHRBALDH1A1
SCHEMBL814048 0.84 TSHR (0.58) TSHRTHRBALDH1A1
SCHEMBL1852500 0.81 TSHR (0.50) TSHRTHRBALDH1A1
SCHEMBL9063433 0.81 TSHR (0.50) TSHRTHRBALDH1A1
SCHEMBL12971262 0.81 TSHR (0.55) TSHRTHRBALDH1A1
SCHEMBL5177573 0.81 TSHR (0.50) TSHRTHRBALDH1A1
SCHEMBL20719918 0.78 TSHR (0.47) TSHRTHRBALDH1A1
SCHEMBL2479915 0.78 TSHR (0.47) TSHRTHRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101369098-B Curing resin composition, sealing material for liquid crystal display device and liquid crystal display device SEKISUI CHEMICAL CO LTD 2012-01-04 CN disclosed
CN-101369098-A Curing resin composition, sealing material for liquid crystal display device and liquid crystal display device SEKISUI CHEMICAL CO LTD (JP) 2009-02-18 CN disclosed
CN-100365793-C Adhesive sheet for processing semiconductor and semiconductor processing method NITTO DENKO CORP (JP) 2008-01-30 CN disclosed
CN-1606144-A Adhesive sheet for processing semiconductor and semiconductor processing method NITTO DENKO CORP (JP) 2005-04-13 CN disclosed
US-6663668-B1 Interpenetrating polymer networks comprising acrylated polydimethylsiloxane membranes used as contact lenses NOVARTIS AG (CH) 2003-12-16 US disclosed
EP-0944658-B1 POROUS POLYORGANOSILOXANE POLYMERS NOVARTIS AG (CH) 2003-06-25 EP disclosed
EP-0944658-A1 POROUS POLYORGANOSILOXANE POLYMERS Novartis AG (CH) 1999-09-29 EP disclosed
WO-1998025982-A1 POROUS POLYORGANOSILOXANE POLYMERS NOVARTIS AG (CH) 1998-06-18 WO disclosed