SCHEMBL7130429

SCHEMBL7130429

O=C(CCN1CCOCC1)N1CCOCC1

nearest known ligand 0.62

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GLA P06280 2/20 0.62
TSHR P16473 2/20 0.59
ALOX15 P16050 1/20 0.59
HSD17B10 Q99714 1/20 0.59
L3MBTL1 Q9Y468 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
LMNA P02545 1/20 0.51
POLB P06746 1/20 0.51
ALDH1A1 P00352 5/20 0.50
MAPT P10636 3/20 0.50
KMT2A Q03164 3/20 0.50
FKBP1A P62942 1/20 0.50
HTR1A P08908 1/20 0.49
HTR7 P34969 1/20 0.49
KDM1A O60341 1/20 0.48
RAB9A P51151 1/20 0.47
KDM4E B2RXH2 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7130414 0.96 HSD17B10 (0.64) GLATSHRALOX15HSD17B10L3MBTL1
Sulfuric Acid SCHEMBL30521499 0.93 GLA (0.55) GLATSHRALOX15HSD17B10L3MBTL1
SCHEMBL27976382 0.92 GLA (0.53) GLATSHRALOX15HSD17B10L3MBTL1
SCHEMBL27976384 0.87 TSHR (0.53) GLATSHRALOX15HSD17B10L3MBTL1
SCHEMBL28255275 0.87 SMN1; SMN2 (0.50) GLATSHRALOX15HSD17B10L3MBTL1
SCHEMBL9432621 0.87 GLA (0.49) GLATSHRALOX15HSD17B10L3MBTL1
SCHEMBL3459566 0.87 GLA (0.49) GLATSHRALOX15HSD17B10L3MBTL1
SCHEMBL14627467 0.86 TSHR (0.53) GLATSHRALOX15HSD17B10L3MBTL1
SCHEMBL27976711 0.84 NPC1 (0.54) GLATSHRALOX15HSD17B10L3MBTL1
SCHEMBL13043930 0.83 HRH3 (0.51) GLATSHRALOX15HSD17B10SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107417644-B Preparation method of acrylamide compound 深圳有为技术控股集团有限公司 2023-09-12 CN claimed
CN-108947937-B Co-production preparation method of acrylamide and formamide type compound 深圳有为技术控股集团有限公司 2023-05-16 CN claimed
EP-3613727-B1 PREPARATION METHOD FOR CO-PRODUCING ACRYLAMIDE AND FORMAMIDE COMPOUNDS SHENZHEN UV CHEM TECH INC (CN) 2022-03-16 EP claimed
US-10647659-B2 Process for productions of formamides and acrylamides SHENZHEN YOUWEI TECHNOLOGY HOLDINGS GROUP CO., LTD. (CN) 2020-05-12 US claimed
EP-3613727-A1 PREPARATION METHOD FOR CO-PRODUCING ACRYLAMIDE AND FORMAMIDE COMPOUNDS Shenzhen UV-Chem Tech Inc (CN) 2020-02-26 EP claimed
US-20200048186-A1 Process for Productions of Formamides and Acrylamides SHENZHEN YOUWEI TECHNOLOGY HOLDINGS GROUP CO.,LTD. (CN) 2020-02-13 US claimed
US-20250109363-A1 COMPOSITION CONTAINING HIGHLY SAFE AMIDE COMPOUND KJ CHEMICALS CORPORATION (JP) 2025-04-03 US disclosed
EP-4491674-A1 COMPOSITION CONTAINING HIGHLY SAFE AMIDE COMPOUND KJ Chemicals Corporation (JP) 2025-01-15 EP disclosed
CN-117946032-A Novel efficient preparation method of acrylamide compound 深圳有为技术控股集团有限公司 2024-04-30 CN disclosed
CN-117777059-A Preparation method of acrylamide compound 深圳有为技术控股集团有限公司 2024-03-29 CN disclosed
CN-117050037-A Preparation method of acrylamide compound 深圳有为技术控股集团有限公司 2023-11-14 CN disclosed
CN-116925010-A Process for preparing acrylamide compound and its mixture by mixed anhydride method 深圳有为技术控股集团有限公司 2023-10-24 CN disclosed
WO-2023171679-A1 COMPOSITION CONTAINING HIGHLY SAFE AMIDE COMPOUND KJケミカルズ株式会社 2023-09-14 WO disclosed
CN-107973759-A A kind of preparation method of acryloyl morpholine 湖南久日新材料有限公司 2018-05-01 CN disclosed
CN-103880575-B Method for preparing beta-amino amide derivatives UNIV TAIZHOU 2015-06-03 CN disclosed
CN-103880575-A Method for preparing beta-amino amide derivatives UNIV TAIZHOU 2014-06-25 CN disclosed
US-6506939-B1 Producing N-substituted acrylamides and tertiary amines CIBA SPECIALTY CHEMICALS WATER TREATMENTS LTD. (GB) 2003-01-14 US disclosed
CN-1345302-A Method for producing acrylic acid monomer CIBA SPEC CHEM WATER TREAT LTD (GB) 2002-04-17 CN disclosed
EP-1140797-A1 PRODUCTION OF ACRYLIC MONOMERS Ciba Specialty Chemicals Water Treatments Limited (GB) 2001-10-10 EP disclosed
WO-2000041996-A1 PRODUCTION OF ACRYLIC MONOMERS CIBA SPECIALTY CHEMICALS WATER TREATMENTS LIMITED (GB) 2000-07-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10647659-B2 Process for productions of formamides and acrylamides PFAS, FASN, AGPS GLA 1189/4885TSHR 4795/4885ALOX15 284/4885
US-20200048186-A1 Process for Productions of Formamides and Acrylamides PFAS, FASN, AGPS GLA 1189/4885TSHR 4795/4885ALOX15 284/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.