SCHEMBL7130458

SCHEMBL7130458

CCCCCCN(CCCCCC)Cc1cccc(CN(CCCCCC)CCCCCC)c1

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 5/20 0.54
BCHE P06276 5/20 0.53
DRD2 P14416 2/20 0.53
OPRM1 P35372 2/20 0.53
DRD3 P35462 2/20 0.53
OPRD1 P41143 2/20 0.53
OPRK1 P41145 2/20 0.53
MAPT P10636 1/20 0.50
GRIN2D O15399 1/20 0.49
GRIN3B O60391 1/20 0.49
GRIN1 Q05586 1/20 0.49
GRIN2A Q12879 1/20 0.49
GRIN2B Q13224 1/20 0.49
GRIN2C Q14957 1/20 0.49
GRIN3A Q8TCU5 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8722891 0.93 KCNH2 (0.60) KCNH2BCHEDRD2OPRM1DRD3
SCHEMBL7764345 0.93 KCNH2 (0.60) KCNH2BCHEDRD2OPRM1DRD3
SCHEMBL7766004 0.93 KCNH2 (0.60) KCNH2BCHEDRD2OPRM1DRD3
SCHEMBL8720381 0.93 KCNH2 (0.60) KCNH2BCHEDRD2OPRM1DRD3
SCHEMBL8723382 0.93 KCNH2 (0.60) KCNH2BCHEDRD2OPRM1DRD3
SCHEMBL8720400 0.93 KCNH2 (0.60) KCNH2BCHEDRD2OPRM1DRD3
SCHEMBL7764447 0.93 KCNH2 (0.60) KCNH2BCHEDRD2OPRM1DRD3
SCHEMBL10991921 0.92 KCNH2 (0.47) KCNH2BCHEDRD2OPRM1DRD3
SCHEMBL11583950 0.92 KCNH2 (0.47) KCNH2BCHEDRD2OPRM1DRD3
SCHEMBL13060688 0.87 CALM1 (0.48) KCNH2BCHEDRD2OPRM1DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6664224-B2 Microbiocides; sterilization TOAGOSEI CO., LTD. (JP) 2003-12-16 US disclosed
US-20020006888-A1 Novel quaternary ammonium salt and process for the preparation thereof TOAGOSEI CO., LTD. 2002-01-17 US disclosed
EP-1156030-A1 Novel quaternary ammonium salt and process for the preparation thereof TOAGOSEI CO., LTD. (JP) 2001-11-21 EP disclosed