Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7130588 | 1.00 | SLC6A3 (0.52) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7121108 | 0.87 | SLC6A3 (0.65) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7121114 | 0.87 | SLC6A3 (0.65) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7130698 | 0.85 | SLC6A3 (0.56) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7130697 | 0.85 | SLC6A3 (0.56) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7125482 | 0.82 | SLC6A3 (0.67) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7125476 | 0.82 | SLC6A3 (0.67) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7131525 | 0.78 | SLC6A3 (0.51) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7131530 | 0.78 | SLC6A3 (0.51) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL16592158 | 0.77 | SLC6A3 (0.79) | SLC6A3SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6670375-B2 | Particularly, 8-aza-, 8-carbo- and 8-oxo- tropanes having 6-or 7-substituents; preferred are the dopamine transporter, the serotonin transporter and the norepinephrine transporter. | ORGANIX, INC. | 2003-12-30 | — | — | US | claimed |