SCHEMBL713258

SCHEMBL713258

COc1ccccc1C=Cc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NFE2L2 Q16236 7/20 1.00
▸ TRPA1 O75762 2/20 1.00
▸ CYP1A1 P04798 5/20 0.69
▸ CYP1A2 P05177 5/20 0.69
▸ CYP1B1 Q16678 5/20 0.69
▸ CYP19A1 P11511 1/20 0.68
▸ ALOX5 P09917 1/20 0.62
▸ PTGS1 P23219 1/20 0.62
▸ PTGS2 P35354 1/20 0.62
▸ TUBB1 Q9H4B7 2/20 0.58
▸ TUBB4A P04350 1/20 0.58
▸ TUBB P07437 1/20 0.58
▸ TUBA3C P0DPH7 1/20 0.58
▸ TUBA1B P68363 1/20 0.58
▸ TUBA4A P68366 1/20 0.58
▸ TUBB4B P68371 1/20 0.58
▸ TUBB3 Q13509 1/20 0.58
▸ TUBB2A Q13885 1/20 0.58
▸ TUBB8 Q3ZCM7 1/20 0.58
▸ TUBA3E Q6PEY2 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL713256 1.00 NFE2L2 (1.00) NFE2L2TRPA1CYP1A1CYP1A2CYP1B1
SCHEMBL9168170 0.94 NFE2L2 (0.88) NFE2L2TRPA1CYP1A1CYP1A2CYP1B1
SCHEMBL9168164 0.94 NFE2L2 (0.88) NFE2L2TRPA1CYP1A1CYP1A2CYP1B1
SCHEMBL1603719 0.89 NFE2L2 (0.79) NFE2L2TRPA1CYP1A1CYP1A2CYP1B1
SCHEMBL4019329 0.89 NFE2L2 (0.79) NFE2L2TRPA1CYP1A1CYP1A2CYP1B1
SCHEMBL7915752 0.89 NFE2L2 (0.79) NFE2L2TRPA1CYP1A1CYP1A2CYP1B1
SCHEMBL29547034 0.88 NFE2L2 (0.79) NFE2L2TRPA1CYP1A1CYP1A2CYP1B1
SCHEMBL178754 0.88 NFE2L2 (0.79) NFE2L2TRPA1CYP1A1CYP1A2CYP1B1
SCHEMBL553331 0.88 NFE2L2 (0.79) NFE2L2TRPA1CYP1A1CYP1A2CYP1B1
SCHEMBL28715871 0.86 NFE2L2 (0.76) NFE2L2TRPA1CYP1A1CYP1A2CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105541566-A Method for synthesizing 1-benzyloxy-2-[2-(3-methoxyphenyl)vinyl]benzene SUZHOU CHENGHE PHARMACEUTICAL & CHEMICAL CO LTD 2016-05-04 — — CN claimed
CN-105541564-A New method for synthesizing 1-benzyloxy-2-[2-(3-methoxyphenyl)vinyl]benzene SUZHOU CHENGHE PHARMACEUTICAL & CHEMICAL CO LTD 2016-05-04 — — CN claimed
CN-105541569-A Synthesis method of 1-benzyloxy-2-[2-(3-methoxyphenyl)vinyl]benzene SUZHOU CHENGHE PHARMACEUTICAL & CHEMICAL CO LTD 2016-05-04 — — CN claimed
CN-105439828-A Method for synthesizing 1-benzyloxy-2-[2-(3-methoxyphenyl) vinyl]benzene SUZHOU CHENGHE PHARMACEUTICAL & CHEMICAL CO LTD 2016-03-30 — — CN claimed
EP-2875359-A2 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING METABOLIC SYNDROME DISORDERS Charles R Drew University of Medicine and Science (US) 2015-05-27 — — EP claimed
WO-2013149258-A2 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING METABOLIC SYNDROME DISORDERS Charles Drew University of Medicine and Science (US) 2013-10-03 — — WO claimed
EP-2290651-B1 Compositions, optical data storage media and methods for using the optical data storage media GEN ELECTRIC (US) 2012-10-10 — — EP claimed
US-8124299-B2 Methods for using optical data storage media GENERAL ELECTRIC COMPANY (US) 2012-02-28 — — US claimed
US-20110053054-A1 COMPOSITIONS, OPTICAL DATA STORAGE MEDIA AND METHODS FOR USING THE OPTICAL DATA STORAGE MEDIA GENERAL ELECTRIC COMPANY (US) 2011-03-03 — — US claimed
US-20110053055-A1 COMPOSITIONS, OPTICAL DATA STORAGE MEDIA AND METHODS FOR USING THE OPTICAL DATA STORAGE MEDIA GENERAL ELECTRIC COMPANY (US) 2011-03-03 — — US claimed
EP-2290651-A1 Compositions, optical data storage media and methods for using the optical data storage media General Electric Company (US) 2011-03-02 — — EP claimed
US-20100302927-A1 OPTICAL DATA STORAGE MEDIUM AND METHODS FOR USING THE SAME GENERAL ELECTRIC COMPANY (US) 2010-12-02 — — US claimed
US-5530030-A CHLORINATED HYDROXYSTILBENES KIORITZ CORPORATIN (JP) 1996-06-25 — — US claimed
US-5314693-A Hydroxystilbene compounds KIORITZ CORPORATION (JP) 1994-05-24 — — US claimed
CN-1075845-A The pest control chemicals of antagonism pine wood nematodes KIORITZ CORP (JP) 1993-09-08 — — CN claimed
JP-7118107-A — — None — — JP disclosed
JP-5279223-A — — None — — JP disclosed
EP-0041043-A1 Process for the preparation of derivatives of alkenyl benzene or alkenyl naphthalene CIBA-GEIGY AG (CH) 1981-12-02 — — EP disclosed
EP-0024567-A1 2-(4-Aminobutoxy)stilbenes and pharmaceutical compositions comprising these compounds MITSUBISHI KASEI CORPORATION (JP) 1981-03-11 — — EP disclosed
US-3974092-A COMPOUND, 6B, ORGANOALUMINUM COMPOUND, ETHER OF OLEFIN ALCOHOL CHEMISCHE WERKE HULS AKTIENGESELLSCHAFT (DT) 1976-08-10 — — US disclosed
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