Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 15/20 | 0.68 |
| ▸ | SRC | P12931 | 15/20 | 0.68 |
| ▸ | TEK | Q02763 | 15/20 | 0.68 |
| ▸ | KDR | P35968 | 5/20 | 0.68 |
| ▸ | EGFR | P00533 | 5/20 | 0.65 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.65 |
| ▸ | IGF1R | P08069 | 5/20 | 0.65 |
| ▸ | ERBB3 | P21860 | 5/20 | 0.65 |
| ▸ | ERBB4 | Q15303 | 5/20 | 0.65 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.64 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.64 |
| ▸ | FYN | P06241 | 1/20 | 0.61 |
| ▸ | BTK | Q06187 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4847861 | 0.89 | LCK (0.84) | LCKSRCTEKKDREGFR | |
| SCHEMBL4819139 | 0.89 | SRC (0.64) | LCKSRCTEKKDREGFR | |
| SCHEMBL4826702 | 0.87 | LCK (0.69) | LCKSRCTEKKDREGFR | |
| SCHEMBL7136180 | 0.86 | SRC (0.77) | LCKSRCTEKKDREGFR | |
| SCHEMBL4825115 | 0.85 | SRC (0.67) | LCKSRCTEKKDREGFR | |
| SCHEMBL6435519 | 0.85 | SRC (0.67) | LCKSRCTEKKDREGFR | |
| SCHEMBL7142942 | 0.85 | SRC (0.70) | LCKSRCTEKKDREGFR | |
| Acetic Acid SCHEMBL4818446 | 0.85 | LCK (0.61) | LCKSRCTEKKDREGFR | |
| SCHEMBL4828010 | 0.85 | LCK (0.70) | LCKSRCTEKKDREGFR | |
| SCHEMBL5787000 | 0.85 | LCK (0.77) | LCKSRCTEKKDRLIMK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6660744-B1 | Kinase inhibitors | ABBOTT GMBH & CO. KG (DE) | 2003-12-09 | — | — | US | disclosed |