Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.48 |
| ▸ | EGFR | P00533 | 4/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | AGXT | P21549 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10436447 | 0.82 | TAAR1 (0.47) | TAAR1EGFRERBB2IDO1AGXT | |
| SCHEMBL400060 | 0.81 | EGFR (0.50) | TAAR1EGFRERBB2IDO1AGXT | |
| SCHEMBL27362003 | 0.81 | TAAR1 (0.47) | TAAR1EGFRERBB2IDO1AGXT | |
| SCHEMBL78652 | 0.79 | AKR1B1 (0.58) | TAAR1EGFRERBB2HCAR2TDP1 | |
| Hydrochloric Acid SCHEMBL1374336 | 0.78 | AKR1B1 (0.56) | TAAR1EGFRERBB2IDO1AGXT | |
| Methane SCHEMBL10697726 | 0.78 | AKR1B1 (0.56) | TAAR1EGFRERBB2HCAR2TDP1 | |
| SCHEMBL27583682 | 0.78 | EGFR (0.50) | TAAR1EGFRERBB2IDO1AGXT | |
| SCHEMBL31208443 | 0.77 | EGFR (0.50) | TAAR1EGFRERBB2 | |
| SCHEMBL1448505 | 0.77 | EGFR (0.53) | TAAR1EGFRERBB2IDO1AGXT | |
| SCHEMBL9294120 | 0.77 | TAAR1 (0.50) | TAAR1EGFRERBB2IDO1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6509476-B1 | Leukotriene antagonists; antiallergens, antiinflammatory agents, and antiasthmatic agents | THE UNIVERSITY OF EAST ANGLIA (GB) | 2003-01-21 | — | — | US | disclosed |
| US-6160120-A | Process for preparing n-benzyl indoles | ELI LILLY AND COMPANY (US) | 2000-12-12 | — | — | US | disclosed |
| US-5807866-A | Process for preparing N-benzyl indoles | THE UNIVERSITY OF EAST ANGLIA (GB) | 1998-09-15 | — | — | US | disclosed |
| EP-0775694-A2 | Process for preparing N-benzyl indoles | University of East Anglia (GB) | 1997-05-28 | — | — | EP | disclosed |