Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | AGXT | P21549 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | EGFR | P00533 | 4/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7134071 | 0.81 | TAAR1 (0.48) | TAAR1IDO1AGXTMAOBEGFR | |
| SCHEMBL8215471 | 0.80 | EGFR (0.46) | TAAR1MAOBEGFRERBB2CYP1A2 | |
| SCHEMBL10436447 | 0.79 | TAAR1 (0.47) | TAAR1IDO1AGXTMAOBEGFR | |
| SCHEMBL136054 | 0.79 | SLC7A5 (0.55) | TAAR1MAOBEGFRERBB2CYP1A2 | |
| SCHEMBL29700723 | 0.79 | SLC7A5 (0.55) | TAAR1MAOBEGFRERBB2CYP1A2 | |
| SCHEMBL14565973 | 0.77 | AGXT (0.47) | AGXT | |
| SCHEMBL13176469 | 0.77 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7641680 | 0.76 | EGFR (0.51) | TAAR1IDO1AGXTMAOBEGFR | |
| SCHEMBL16953485 | 0.75 | TAAR1 (0.43) | TAAR1IDO1AGXTMAOBEGFR | |
| SCHEMBL9294120 | 0.75 | TAAR1 (0.50) | TAAR1IDO1AGXTMAOBEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024038378-A1 | SUBSTITUTED PYRIDINONE COMPOUNDS AS CBL-B INHIBITORS | GLENMARK PHARMACEUTICALS LTD (IN) | 2024-02-22 | — | — | WO | disclosed |