Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.57 |
| ▸ | PTGER3 | P43115 | 14/20 | 0.57 |
| ▸ | PTGER2 | P43116 | 13/20 | 0.57 |
| ▸ | PTGER4 | P35408 | 11/20 | 0.57 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.57 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.57 |
| ▸ | PTGFR | P43088 | 3/20 | 0.57 |
| ▸ | PTGER1 | P34995 | 5/20 | 0.56 |
| ▸ | PTGIR | P43119 | 2/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3214322 | 0.87 | PTGER3 (0.63) | PTGER3PTGER2PTGER4PTGDRTBXA2R | |
| SCHEMBL309761 | 0.87 | PTGER3 (0.63) | PTGER3PTGER2PTGER4PTGDRTBXA2R | |
| SCHEMBL1150939 | 0.87 | PTGER3 (0.63) | PTGER3PTGER2PTGER4PTGDRTBXA2R | |
| SCHEMBL3685249 | 0.83 | EGFR (0.53) | EGFRPTGER3PTGER2PTGER4PTGDR | |
| SCHEMBL3685251 | 0.83 | EGFR (0.53) | EGFRPTGER3PTGER2PTGER4PTGDR | |
| Methacrylic Acid SCHEMBL10714797 | 0.79 | PTGER3 (0.54) | PTGER3PTGER2PTGER4PTGDRTBXA2R | |
| SCHEMBL5873000 | 0.78 | CA1 (0.53) | PTGER3PTGER2PTGER4PTGDRTBXA2R | |
| SCHEMBL5007834 | 0.78 | PTGER3 (0.52) | PTGER3PTGER2PTGER4PTGDRTBXA2R | |
| SCHEMBL8125134 | 0.77 | EGFR (0.50) | EGFRPTGER3PTGER2PTGER4PTGDR | |
| SCHEMBL8125136 | 0.77 | EGFR (0.50) | EGFRPTGER3PTGER2PTGER4PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6509506-B1 | Asymmetric aminohydroxylation of olefins using osmium catalyst; oxidation | THE SCRIPPS RESEARCH INSTITUTE | 2003-01-21 | — | — | US | disclosed |
| WO-1997044312-A9 | TWO STEP SYNTHESIS OF D- AND L- α-AMINO ACIDS AND D- AND L- α-AMINO ALDEHYDES | — | 1998-03-12 | — | — | WO | disclosed |
| WO-1997044312-A1 | TWO STEP SYNTHESIS OF D- AND L- α-AMINO ACIDS AND D- AND L- α-AMINO ALDEHYDES | THE SCRIPPS RESEARCH INSTITUTE (US) | 1997-11-27 | — | — | WO | disclosed |