SCHEMBL3214322

SCHEMBL3214322

CCc1ccccc1/C=C\C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER3 P43115 12/20 0.63
PTGER2 P43116 11/20 0.63
PTGER4 P35408 9/20 0.63
PTGDR Q13258 5/20 0.59
TBXA2R P21731 4/20 0.59
CA1 P00915 1/20 0.58
CA2 P00918 1/20 0.58
NFKB1 P19838 1/20 0.58
CA4 P22748 1/20 0.58
PTGFR P43088 3/20 0.56
PTGER1 P34995 4/20 0.56
PTGIR P43119 2/20 0.55
TBXAS1 P24557 1/20 0.52
HDAC3 O15379 1/20 0.50
TNKS O95271 1/20 0.50
HDAC4 P56524 1/20 0.50
HDAC1 Q13547 1/20 0.50
HCAR2 Q8TDS4 1/20 0.50
HDAC7 Q8WUI4 1/20 0.50
HDAC2 Q92769 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL309761 1.00 PTGER3 (0.63) PTGER3PTGER2PTGER4PTGDRTBXA2R
SCHEMBL1150939 1.00 PTGER3 (0.63) PTGER3PTGER2PTGER4PTGDRTBXA2R
Methacrylic Acid SCHEMBL10714797 0.90 PTGER3 (0.54) PTGER3PTGER2PTGER4PTGDRTBXA2R
SCHEMBL5007834 0.89 PTGER3 (0.52) PTGER3PTGER2PTGER4PTGDRTBXA2R
SCHEMBL7134072 0.87 EGFR (0.57) PTGER3PTGER2PTGER4PTGDRTBXA2R
SCHEMBL28893816 0.87 PTGER3 (0.58) PTGER3PTGER2PTGER4PTGDRTBXA2R
SCHEMBL3256824 0.87 PTGER3 (0.58) PTGER3PTGER2PTGER4PTGDRTBXA2R
SCHEMBL7499883 0.86 NFKB1 (0.60) PTGER3PTGER2PTGER4PTGDRTBXA2R
SCHEMBL5873000 0.86 CA1 (0.53) PTGER3PTGER2PTGER4PTGDRTBXA2R
SCHEMBL12075162 0.85 LMNA (0.61) PTGER3PTGER2PTGER4PTGDRTBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8279435-B2 Nanostructured metal-polyaniline composites and applications thereof LOS ALAMOS NATIONAL SECURITY, LLC (US) 2012-10-02 US disclosed
US-7786037-B2 Silver, gold, platinum, palladium; porous asymmetric membrane; acidic dopant of hydrochloric acid, phosphoric acid, citric acid, madelic acid, trifluoroacetic acid, para-toluenesulfonic; metal salt has reduction potential greater than polyaniline; easily recovered, reused hydrogenation catalyst LOS ALAMOS NATIONAL SECURITY, LLC (US) 2010-08-31 US disclosed
US-20100060894-A1 NANOSTRUCTURED METAL-POLYANILINE COMPOSITES AND APPLICATIONS THEREOF LOS ALAMOS NATIONAL SECURITY, LLC (US) 2010-03-11 US disclosed
US-20080171656-A1 Nanostructured metal-polyaniline composites ENERGY, U.S. DEPARTMENT OF 2008-07-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100060894-A1 NANOSTRUCTURED METAL-POLYANILINE COMPOSITES AND APPLICATIONS THEREOF PARG, PARN, FHIT PTGER3 3806/4885PTGER2 4206/4885PTGER4 4394/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.