Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 6/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | NMT2 | O60551 | 1/20 | 0.30 |
| ▸ | NMT1 | P30419 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7134238 | 1.00 | BMP1 (0.37) | BMP1MMP1MMP3MMP13NAAA | |
| SCHEMBL7134245 | 1.00 | BMP1 (0.37) | BMP1MMP1MMP3MMP13NAAA | |
| SCHEMBL5761682 | 0.89 | BMP1 (0.38) | BMP1MMP1MMP3MMP13 | |
| SCHEMBL5761695 | 0.89 | BMP1 (0.38) | BMP1MMP1MMP3MMP13 | |
| SCHEMBL5761692 | 0.89 | BMP1 (0.38) | BMP1MMP1MMP3MMP13 | |
| SCHEMBL5418960 | 0.87 | BMP1 (0.37) | BMP1MMP1MMP3MMP13MEN1 | |
| SCHEMBL5415570 | 0.87 | BMP1 (0.37) | BMP1MMP1MMP3MMP13MEN1 | |
| SCHEMBL5760308 | 0.79 | BMP1 (0.38) | BMP1MMP1MMP3MMP13 | |
| SCHEMBL5760320 | 0.79 | BMP1 (0.38) | BMP1MMP1MMP3MMP13 | |
| SCHEMBL5760317 | 0.79 | BMP1 (0.38) | BMP1MMP1MMP3MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343771-A1 | 3-OX(ADI)AZOLYLPROPANOHYDROXAMIC ACIDS USEFUL AS PROCOLLAGEN C-PROTEINASE INHIBITORS | Pfizer Limited (GB) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002050046-A1 | 3-OX(ADI)AZOLYLPROPANOHYDROXAMIC ACIDS USEFUL AS PROCOLLAGEN C-PROTEINASE INHIBITORS | PFIZER LIMITED (GB) | 2002-06-27 | — | — | WO | disclosed |