Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.62 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.54 |
| ▸ | NAAA | Q02083 | 1/20 | 0.53 |
| ▸ | PAM | P19021 | 2/20 | 0.53 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.51 |
| ▸ | P2RY10 | O00398 | 4/20 | 0.50 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.49 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30893654 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3NAAA | |
| SCHEMBL31222042 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3NAAA | |
| SCHEMBL31647193 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3NAAA | |
| SCHEMBL8359802 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3NAAA | |
| SCHEMBL21465347 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3NAAA | |
| SCHEMBL22973781 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3NAAA | |
| SCHEMBL30893651 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3NAAA | |
| SCHEMBL8820849 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3NAAA | |
| SCHEMBL8356466 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3NAAA | |
| SCHEMBL31058419 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6503526-B1 | Absorbent articles enhancing skin barrier function | KIMBERLY-CLARK WORLDWIDE, INC. | 2003-01-07 | — | — | US | disclosed |
| WO-2002034305-A2 | ABSORBENT ARTICLES ENHANCING SKIN BARRIER FUNCTION | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2002-05-02 | — | — | WO | disclosed |