Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzenethiol SCHEMBL3902726 | 0.93 | KMT2A (0.39) | ALDH1A1HSD17B10HPGDBCL2L1CYP2A6 | |
| SCHEMBL164357 | 0.92 | ALDH1A1 (0.48) | ALDH1A1HSD17B10HPGDBCL2L1CYP2A6 | |
| SCHEMBL27455692 | 0.90 | ALDH1A1 (0.46) | ALDH1A1HSD17B10HPGDBCL2L1CYP2A6 | |
| SCHEMBL27326199 | 0.90 | ALDH1A1 (0.46) | ALDH1A1HSD17B10HPGDBCL2L1CYP2A6 | |
| Biphenyl SCHEMBL3199503 | 0.90 | ALDH1A1 (0.50) | ALDH1A1HSD17B10HPGDBCL2L1CYP2A6 | |
| SCHEMBL3893272 | 0.90 | ALDH1A1 (0.46) | ALDH1A1HSD17B10HPGDBCL2L1CYP2A6 | |
| Biphenyl SCHEMBL16581537 | 0.87 | ALDH1A1 (0.47) | ALDH1A1HSD17B10HPGDBCL2L1CYP2A6 | |
| SCHEMBL22931425 | 0.87 | IDO1 (0.38) | ALDH1A1HSD17B10HPGDBCL2L1CYP2A6 | |
| SCHEMBL12609346 | 0.87 | ALDH1A1 (0.47) | ALDH1A1HSD17B10HPGDBCL2L1CYP2A6 | |
| SCHEMBL4812560 | 0.86 | MEN1 (0.39) | ALDH1A1HSD17B10HPGDBCL2L1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6511947-B1 | A mixture of a polyphenyl ether having 4-5 aromatic rings and/or its hydrocarbon substituted group with a polyphenyl thioether having 3-5 aromatic rings, an amine antioxidant, a phosphate, and an amine salt of acid phosphate | TONEN GENERAL SEKIYU K.K. (JP) | 2003-01-28 | — | — | US | disclosed |