Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.68 |
| ▸ | KIT | P10721 | 1/20 | 0.68 |
| ▸ | FLT3 | P36888 | 1/20 | 0.68 |
| ▸ | EGFR | P00533 | 6/20 | 0.58 |
| ▸ | LCK | P06239 | 3/20 | 0.58 |
| ▸ | ITK | Q08881 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6430186 | 0.95 | BTK (0.74) | BTKKITFLT3EGFRLCK | |
| SCHEMBL6645874 | 0.88 | BTK (0.85) | BTKKITFLT3EGFRLCK | |
| Acetic Acid SCHEMBL5819970 | 0.86 | BTK (0.82) | BTKKITFLT3EGFRLCK | |
| Acetic Acid SCHEMBL6430451 | 0.86 | BTK (0.66) | BTKKITFLT3EGFRLCK | |
| Acetic Acid SCHEMBL5805244 | 0.85 | BTK (0.63) | BTKKITFLT3EGFRLCK | |
| Acetic Acid SCHEMBL6430809 | 0.83 | BTK (0.67) | BTKKITFLT3EGFRLCK | |
| SCHEMBL17951520 | 0.83 | BTK (0.92) | BTKKITFLT3EGFRLCK | |
| SCHEMBL6438133 | 0.82 | BTK (0.73) | BTKKITFLT3EGFRLCK | |
| SCHEMBL7139894 | 0.82 | BTK (0.68) | BTKKITFLT3EGFRLCK | |
| SCHEMBL7144296 | 0.81 | BTK (0.73) | BTKFLT3EGFRLCKITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6660744-B1 | Kinase inhibitors | ABBOTT GMBH & CO. KG (DE) | 2003-12-09 | — | — | US | disclosed |