Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 3/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL715856 | 0.77 | MAPT (0.42) | KMT2AALDH1A1KDM4EHPGDKDR | |
| SCHEMBL715062 | 0.77 | SLC6A2 (0.40) | KMT2AALDH1A1KDM4ETSHRNOTUM | |
| SCHEMBL1878805 | 0.75 | HAO1 (0.58) | KMT2AHAO1L3MBTL1APPALDH1A1 | |
| SCHEMBL1753892 | 0.75 | KMT2A (0.58) | KMT2AHAO1L3MBTL1APPALDH1A1 | |
| SCHEMBL13425022 | 0.75 | HAO1 (0.62) | KMT2AHAO1L3MBTL1APPALDH1A1 | |
| SCHEMBL713626 | 0.75 | HAO1 (0.52) | KMT2AHAO1L3MBTL1APPALDH1A1 | |
| SCHEMBL13425013 | 0.73 | KMT2A (0.55) | KMT2AHAO1L3MBTL1APPALDH1A1 | |
| SCHEMBL3867353 | 0.73 | HAO1 (0.59) | KMT2AHAO1L3MBTL1APPALDH1A1 | |
| SCHEMBL715245 | 0.72 | HAO1 (0.49) | KMT2AHAO1L3MBTL1APPALDH1A1 | |
| SCHEMBL12979892 | 0.71 | HAO1 (0.58) | KMT2AHAO1L3MBTL1APPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8771843-B2 | Fluorene derivative, organic compound, and light-emitting element, light-emitting device, and electronic device using the compound | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2014-07-08 | — | — | US | disclosed |
| US-20120049768-A1 | Fluorene Derivative, Organic Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Compound | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120049768-A1 | Fluorene Derivative, Organic Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Compound | AFF2, MAPRE2, AFF4 | KMT2A 2499/4885HAO1 2831/4885L3MBTL1 988/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.