MAPRE2

Microtubule-associated protein RP/EB family member 2 · Q15555 · MAPRE2 on Sugi Atlas →

0 patent compounds predicted against MAPRE2, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to MAPRE2 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU) PHASE2/PHASE3ACTIVE_NOT_RECRUITING
Management of Retinitis Pigmentosa Via Combination of Wharton's Jelly-derived Mesenchymal Stem Cells and Magnovision PHASE3COMPLETED
4D-125 in Patients With X-Linked Retinitis Pigmentosa (XLRP) PHASE1/PHASE2ACTIVE_NOT_RECRUITING
A Phase 1/2, First-in-Human Dose Escalation/Expansion Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of a Subretinal Injection of SB-007 in Subjects With Stargardt Disease (STGD1) PHASE1/PHASE2RECRUITING
Safety and Efficacy of AAV9/AP4B1 (BFB-101) For Patients With AP4B1-related Hereditary Spastic Paraplegia Type 47 (SPG47) PHASE1/PHASE2NOT_YET_RECRUITING
Study of Oral Minocycline in Treating Bilateral Cystoid Macular Edema Associated With Retinitis Pigmentosa PHASE1/PHASE2COMPLETED
Intravitreal Adalimumab in Inherited and Degenerative Retinal Diseases PHASE1/PHASE2ACTIVE_NOT_RECRUITING
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt) PHASE1/PHASE2RECRUITING
Intravitreal Dexamethasone Implant in Retinitis Pigmentosa-related Macular Edema- a Retrospective Study PHASE2UNKNOWN
Investigating the Effect of Vitamin A Supplementation on Retinitis Pigmentosa PHASE1COMPLETED
Study of ABT-751 in Patients With Refractory Hematologic Malignancies PHASE1COMPLETED
Evaluation of Safety of Ciliary Neurotrophic Factor Implants in the Eye PHASE1COMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
InsightRP2 Registry nanRECRUITING
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases nanUNKNOWN
Clinical Characterization on PDE6A-related Retinitis Pigmentosa in Preparation to a Gene Therapy Trial nanCOMPLETED
Mechanisms of Inherited Retinal Dystrophies Using Whole Genome Sequencing and in Vitro and in Vivo Models nanCOMPLETED
Identification of New FTLD Genes nanUNKNOWN
Biomarkers in Retinitis Pigmentosa nanUNKNOWN
Assessing the Polygenic Burden of Rare Disruptive Mutations in Parkinson's Disease nanUNKNOWN
ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD) nanRECRUITING
Autophagy Bladder Cancer nanUNKNOWN
Effects of Subtenon-injected Autologous Platelet-rich Plasma on Visual Functions in Eyes With Retinitis Pigmentosa nanCOMPLETED
Natural History Study of Patients With X-linked Retinal Dystrophy Associated With Mutations in Retinitis Pigmentosa GTPase Regulator (RPGR) nanCOMPLETED
Evaluation of the Genetics of Bipolar Disorder nanACTIVE_NOT_RECRUITING
Neurofilament Surveillance Project (NSP) nanACTIVE_NOT_RECRUITING
Management of Cystoid Macular Edema Secondary to Retinitis Pigmentosa Via Subliminal Micropulse Yellow Laser nanCOMPLETED
Generating Intervals of Reference FFor Early Life Brain Biomarkers. nanRECRUITING
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus nanCOMPLETED
Evaluation of a Novel PET Radioligand to Image OGA nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a MAPRE2 binder may also engage these)

ProteinNameSimilarity
Q5R4I6 1.000 Q5R4I6 →
Q3B8Q0 1.000 Q3B8Q0 →
Q8R001 1.000 Q8R001 →
Q5ZKK1 1.000 Q5ZKK1 →
Q7ZXP1 1.000 Q7ZXP1 →
Q3SZP2 1.000 Q3SZP2 →
Q10113 0.976 Q10113 →
Q9FGQ6 0.973 Q9FGQ6 →
Q3SYW6 0.972 Q3SYW6 →
Q28Z41 0.972 Q28Z41 →
B4HMY3 0.972 B4HMY3 →
B4LNA1 0.972 B4LNA1 →
Q9FJJ5 0.972 Q9FJJ5 →
B4KN00 0.971 B4KN00 →
Q99L45 0.971 Q99L45 →
P40013 0.971 P40013 →
B4P562 0.971 B4P562 →
Q6P1V4 0.971 Q6P1V4 →
B3NML0 0.971 B3NML0 →
ARFGEF1 Brefeldin A-inhibited guanine nucleotide-exchange protein 1 0.971 landscape →
EIF3C Eukaryotic translation initiation factor 3 subunit C 0.971 landscape →
Q9VUC6 0.971 Q9VUC6 →
P87253 0.971 P87253 →
B5ME19 0.971 B5ME19 →
Q7PQ25 0.971 Q7PQ25 →
Q8CCP0 0.970 Q8CCP0 →
A2APV2 0.970 A2APV2 →
Q4WPW2 0.970 Q4WPW2 →
Q4QR58 0.970 Q4QR58 →
Q5BBV4 0.970 Q5BBV4 →