Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 16/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 15/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.35 |
| ▸ | WNT3A | P56704 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7136310 | 0.85 | PTGS2 (0.47) | PTGS2PTGS1ALOX5CTNNB1WNT3A | |
| SCHEMBL7137506 | 0.82 | PTGS2 (0.56) | PTGS2PTGS1ALOX5CTNNB1WNT3A | |
| SCHEMBL7134569 | 0.81 | PTGS2 (0.58) | PTGS2PTGS1ALOX5CTNNB1WNT3A | |
| SCHEMBL4851347 | 0.79 | CTNNB1 (0.36) | PTGS2PTGS1CTNNB1WNT3A | |
| SCHEMBL19810406 | 0.76 | PTGS1 (0.42) | PTGS2PTGS1 | |
| SCHEMBL4613343 | 0.76 | PTGS2 (0.55) | PTGS2PTGS1ALOX5 | |
| SCHEMBL4632013 | 0.75 | PTGS2 (0.67) | PTGS2PTGS1ALOX5 | |
| SCHEMBL4613415 | 0.75 | PTGS2 (0.57) | PTGS2PTGS1ALOX5 | |
| SCHEMBL1730419 | 0.75 | PTGS2 (0.38) | PTGS2PTGS1ALOX5 | |
| SCHEMBL12572001 | 0.75 | PTGS1 (0.41) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0907646-B1 | DIHYDROBENZOPYRAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | UNIV VANDERBILT (US) | 2003-05-21 | — | — | EP | disclosed |
| US-6110960-A | FOR TREATING ARTHRITIS AND AS ANALGESIC | THE PROCTER & GAMBLE COMPANY (US) | 2000-08-29 | — | — | US | disclosed |