SCHEMBL7136305

SCHEMBL7136305

O=P.c1ccc(CCc2ccccc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.58
HPGD P15428 1/20 0.58
ALOX15 P16050 1/20 0.58
ALOX12 P18054 1/20 0.58
CASP1 P29466 1/20 0.58
HSD17B10 Q99714 1/20 0.58
MAOA P21397 4/20 0.57
MAOB P27338 4/20 0.57
FFAR1 O14842 1/20 0.56
TDP1 Q9NUW8 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
CYP2A6 P11509 1/20 0.55
HTR2A P28223 1/20 0.55
TAAR1 Q96RJ0 1/20 0.55
LOXL2 Q9Y4K0 1/20 0.55
KEAP1 Q14145 1/20 0.55
KCNH2 Q12809 1/20 0.52
DAO P14920 2/20 0.50
HDAC3 O15379 1/20 0.50
MAPK1 P28482 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL62125 0.89 ALDH1A1 (0.69) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL9741303 0.89 ALDH1A1 (0.69) ALDH1A1HPGDALOX15ALOX12CASP1
Benzene SCHEMBL3440179 0.89 ALDH1A1 (0.69) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL28226072 0.87 ALDH1A1 (0.58) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL27913192 0.87 ALDH1A1 (0.58) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL4648373 0.87 ALDH1A1 (0.58) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL25402413 0.86 ALDH1A1 (0.65) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL7899313 0.86 ALDH1A1 (0.65) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL11747668 0.86 ALDH1A1 (0.65) ALDH1A1HPGDALOX15ALOX12CASP1
Iodide SCHEMBL9705905 0.86 ALDH1A1 (0.65) ALDH1A1HPGDALOX15ALOX12CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118996447-A Phosphine-oxide substituted quinoxaline quinazolinone compound, preparation method and application thereof 南阳师范学院 2024-11-22 CN claimed
EP-2481760-B1 INITIATOR SYSTEM FOR CATIONIC POLYMERIZATION AND POLYMERIZATION METHOD USING SAME CHINA PETROLEUM & CHEM CORP (CN) 2021-05-05 EP claimed
CN-103910758-B The preparation method of a kind of axial chirality dibenzyl phosphine oxide and axial chirality dibenzyl phosphine SUN YAT-SEN UNIVERSITY (CN) 2016-01-20 CN claimed
CN-103910758-A Preparation method of axially chiral biaryl phosphine oxide and axially chiral biaryl phosphine UNIV SUN YAT SEN 2014-07-09 CN claimed
CN-103073578-A Dibenzyl phosphinic acid synthetic method UNIV TSINGHUA 2013-05-01 CN claimed
US-6624322-B1 Reacting ketones, primary amines and phosphorous compound, then oxidizing the aminophosphonate formed using halogen-free acids in water and solvent mixtures having buffers ATOFINA (FR) 2003-09-23 US claimed
CN-115322222-B Photocatalytic preparation method of ((alkylamino) methyl) diphenyl phosphine oxide compound 河南师范大学 2025-03-21 CN disclosed
CN-110194843-B Phosphorus-containing phenoxy resin, resin composition, material for circuit board, and cured product 日铁化学材料株式会社 2023-01-03 CN disclosed
CN-112898738-A Epoxy resin composition, prepreg, laminate, printed wiring board, and cured product using same 日铁化学材料株式会社 2021-06-04 CN disclosed
EP-2481760-B1 INITIATOR SYSTEM FOR CATIONIC POLYMERIZATION AND POLYMERIZATION METHOD USING SAME CHINA PETROLEUM & CHEM CORP (CN) 2021-05-05 EP disclosed
EP-2481759-B1 ISO-OLEFIN POLYMER AND PREPARATION METHOD THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2021-05-05 EP disclosed
CN-112585189-A Phosphorus-containing epoxy resin, epoxy resin composition, prepreg, laminate, material for circuit board, and cured product 日铁化学材料株式会社 2021-03-30 CN disclosed
CN-108350004-B Preparation method of phosphorus-containing cyanohydrin ester 拜耳作物科学股份公司 2021-03-12 CN disclosed
CN-1168743-C Polymer stabilisation by stable free radical ���շ��л�ѧ���޹�˾ 2004-09-29 CN disclosed
CN-1145625-A Polymer stabilisation by stable free radical ATOCHEM ELF SA (FR) 1997-03-19 CN disclosed
US-5414133-A Protected phosphine oxides CIBA-GEIGY CORPORATION (US) 1995-05-09 US disclosed
US-5298663-A Process for the preparation of protected phosphine oxides CIBA-GEIGY CORPORATION (US) 1994-03-29 US disclosed
CN-1019111-B CHELATED LIGANDS USED AS CATALYST FOR LOW PRESSURE CARBOXYLATION AND ITS USE EASTMAN KODAK CO (US) 1992-11-18 CN disclosed
EP-0501702-A2 Process for the preparation of protected phosphine oxides CIBA-GEIGY AG (CH) 1992-09-02 EP disclosed
CN-1032002-A The chelating ligand and the using method thereof that are used for the low pressure carbonylation catalyst EASTMAN KODAK CO (US) 1989-03-29 CN disclosed