SCHEMBL7138306

SCHEMBL7138306

NS(=O)(=O)CC=Cc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.48
PAM P19021 1/20 0.48
CA2 P00918 2/20 0.46
HTR2A P28223 3/20 0.46
PRMT1 Q99873 1/20 0.45
LMNA P02545 1/20 0.44
PPARG P37231 1/20 0.44
NFE2L2 Q16236 1/20 0.44
CA1 P00915 1/20 0.43
CA5A P35218 1/20 0.43
CA9 Q16790 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3398493 1.00 IDO1 (0.48) IDO1PAMCA2HTR2APRMT1
SCHEMBL6465508 0.83 PAM (0.52) IDO1PAMHTR2ALMNAPPARG
SCHEMBL1173055 0.79 PAM (0.48) IDO1PAMHTR2ALMNAPPARG
SCHEMBL2725744 0.79 PAM (0.53) IDO1PAMHTR2ALMNAPPARG
SCHEMBL2872172 0.79 PAM (0.53) IDO1PAMHTR2ALMNAPPARG
SCHEMBL1172422 0.79 PAM (0.48) IDO1PAMHTR2ALMNAPPARG
SCHEMBL15413488 0.79 PAM (0.48) IDO1PAMHTR2ALMNAPPARG
SCHEMBL4842131 0.79 PAM (0.48) IDO1PAMHTR2ALMNAPPARG
SCHEMBL10701251 0.78 PAM (0.47) IDO1PAMHTR2ALMNAPPARG
SCHEMBL10986652 0.78 PAM (0.47) IDO1PAMHTR2ALMNAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1157058-B1 METHOD OF PREPARING NORBORNENE SULFONAMIDE POLYMERS SUMITOMO BAKELITE CO (JP) 2003-06-25 EP disclosed
US-6420503-B1 POLYCARBONS/OTHER/ SUMITOMO BAKELITE CO. LTD. (JP) 2002-07-16 US disclosed
EP-1157058-A1 METHOD OF PREPARING NORBORNENE SULFONAMIDE POLYMERS The B.F. Goodrich Company (US) 2001-11-28 EP disclosed
US-6235849-B1 INCLUDE COPOLYMERS WITH ONE OR MORE COMONOMERS SUCH AS NORBORNENE, ETHYLENE, AN ACRYLATE OR SULFUR DIOXIDE OR CARBON MONOXIDE; ALSO RING-OPENING METATHESIS POLYMERIZATION; GROUP VIII METAL COMPOUND CATALYST THE B. F. GOODRICH COMPANY 2001-05-22 US disclosed
WO-2000046267-A1 METHOD OF PREPARING NORBORNENE SULFONAMIDE POLYMERS THE B.F. GOODRICH COMPANY (US) 2000-08-10 WO disclosed
WO-2000046268-A1 NORBORNENE SULFONAMIDE POLYMERS THE B.F. GOODRICH COMPANY (US) 2000-08-10 WO disclosed