Asparagine

SCHEMBL7138385

CC(C)[C@H](N)C(=O)O.CC(C)[C@H](N)C(=O)O.CC(C)[C@H](N)C(=O)O.CC(C)[C@H](N)C(=O)O.NC(=O)C[C@H](N)C(=O)O.NC(=O)C[C@H](N)C(=O)O.N[C@@H](CS)C(=O)O.N[C@@H](CS)C(=O)O.N[C@@H](CS)C(=O)[O-].N[C@@H](CS)C(=O)[O-].O=C(O)[C@@H]1CCCN1.O=C(O)[C@@H]1CCCN1.[Cu+2]

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SLC5A2

The experimentally established mechanism targets of Asparagine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	PTGS1	P23219	1/20	0.32

▸	SLC7A11	Q9UPY5	1/20	0.32

▸	SLC7A5	Q01650	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Asparagine SCHEMBL7138311	0.98	PTGS1 (0.31)	PTGS1SLC7A11
Asparagine SCHEMBL5664265	0.94	PTGS1 (0.36)	PTGS1SLC7A11SLC7A5
Asparagine SCHEMBL7138389	0.93	PTGS1 (0.36)	PTGS1SLC7A11SLC7A5
Asparagine SCHEMBL6867413	0.92	PTGS1 (0.35)	PTGS1SLC7A11SLC7A5
Asparagine SCHEMBL5665078	0.92	PTGS1 (0.35)	PTGS1SLC7A11SLC7A5
Asparagine SCHEMBL7138313	0.91	PTGS1 (0.34)	PTGS1SLC7A11SLC7A5
Glutamine SCHEMBL6371387	0.90	ALOX15 (0.36)	PTGS1SLC7A11
Valine SCHEMBL3054587	0.90	SLC7A5 (0.34)	PTGS1SLC7A11SLC7A5
Glutamine SCHEMBL6369942	0.89	ALOX15 (0.35)	—
Asparagine SCHEMBL7139781	0.88	PTGS1 (0.32)	PTGS1SLC7A11SLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-6506731-B1	Peptide or peptide-like compound(s) of the present invention appear to aid the elasticity and/or turgor of the skin	CONNECTIVE TISSUE IMAGINEERING LLC	2003-01-14	—	—	US	disclosed