SCHEMBL71391

SCHEMBL71391

O=C(C(F)F)C(F)Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL891416 0.76
SCHEMBL29120955 0.72
Water SCHEMBL434753 0.72
SCHEMBL19972861 0.69
SCHEMBL1421383 0.69
SCHEMBL19972878 0.69
SCHEMBL9805807 0.69
SCHEMBL11464946 0.69
SCHEMBL1512305 0.67
SCHEMBL10477245 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4460 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119977918-A Synthesis method of 2-bromomethyl-5-trifluoromethyl furan 上海高准医药有限公司 2025-05-13 CN claimed
CN-118047967-A Double-cation functionalized fluorine-containing polyarylisatin anion exchange membrane and preparation method thereof 长春工业大学 2024-05-17 CN claimed
CN-117866264-A Polyarylene ion exchange membrane and preparation method thereof 南方科技大学 2024-04-12 CN claimed
CN-117700694-A Cross-linked polymer, binder, ionic membrane, and preparation method and application thereof 宁波中科氢易膜科技有限公司 2024-03-15 CN claimed
CN-109400589-B Quinoxaline bactericide, preparation method and application thereof 湖北文理学院 2020-09-25 CN claimed
CN-109400588-B Fluorine-containing triazole quinoxaline bactericide, preparation method and application thereof 湖北文理学院 2020-09-25 CN claimed
US-20130041054-A1 MATERIAL FOR REMOVING CAUXIN IN CAT URINE NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY 2013-02-14 US claimed
EP-2538216-A1 MATERIAL FOR REMOVING CAUXIN IN CAT URINE National University Corporation Chiba University (JP) 2012-12-26 EP claimed
JP-7165750-A None JP disclosed
EP-4748862-A2 HETERODIMERIC PROTEINS Xencor, Inc. (US) 2026-05-27 EP disclosed
EP-3620473-B1 NOVEL HETERODIMERIC PROTEINS XENCOR INC (US) 2026-05-27 EP disclosed
EP-3865514-B9 BISPECIFIC ANTIBODY BINDING DLL3 AND CD3 AMGEN RES MUNICH GMBH (DE) 2026-05-20 EP disclosed
US-12630650-B2 Engineered IgA antibodies and methods of use TIGATX, INC. (US) 2026-05-19 US disclosed
US-20260132199-A1 ANTIBODY CONSTRUCTS FOR DLL3 AND CD3 AMGEN RES MUNICH GMBH (DE) 2026-05-14 US disclosed
WO-1990007572-A1 HUMAN DNase GENENTECH, INC. (US) 1990-07-12 WO disclosed
EP-0362272-A1 METHOD AND COMPOSITIONS FOR MAKING ACSF AND ACSF ANTAGONISTS. GENENTECH INC (US) 1990-04-11 EP disclosed
EP-0354989-A1 Megakaryocytopoietin, preparation and use YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 1990-02-21 EP disclosed
WO-1989012678-A1 PURIFIED UBIQUITIN HYDROLASE, DNA SEQUENCES ENCODING SAME, AND ITS USE IN RECOVERING POLYPEPTIDES GENENTECH, INC. (US) 1989-12-28 WO disclosed
WO-1988009376-A1 METHOD AND COMPOSITIONS FOR MAKING ACSF AND ACSF ANTAGONISTS GENENTECH, INC. (US) 1988-12-01 WO disclosed
US-4562292-A INHIBITORS OF HYDROLYTIC ENZYMES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1985-12-31 US disclosed