Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 12/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.48 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.48 |
| ▸ | PARP14 | Q460N5 | 3/20 | 0.48 |
| ▸ | TNKS | O95271 | 1/20 | 0.48 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.48 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL36694 | 0.83 | PARP1 (0.73) | PARP1TSHRPOLBCYP3A4MAPT | |
| SCHEMBL31021028 | 0.83 | PARP1 (0.73) | PARP1TSHRPOLBCYP3A4MAPT | |
| Ammonia Solution, Strong SCHEMBL9121446 | 0.80 | PARP1 (0.70) | PARP1TSHRPOLBCYP3A4MAPT | |
| Methane SCHEMBL688609 | 0.80 | PARP1 (0.70) | PARP1TSHRPOLBCYP3A4MAPT | |
| Water SCHEMBL7768285 | 0.80 | PARP1 (0.70) | PARP1TSHRPOLBCYP3A4MAPT | |
| Hydrochloric Acid SCHEMBL1367509 | 0.80 | PARP1 (0.70) | PARP1TSHRPOLBCYP3A4MAPT | |
| SCHEMBL8019600 | 0.79 | CA12 (0.58) | TSHRPOLBMAPTRECQLBLM | |
| Terephthalamide SCHEMBL5692322 | 0.78 | PARP1 (0.67) | PARP1TSHRPOLBCYP3A4MAPT | |
| SCHEMBL2431097 | 0.76 | PARP1 (0.64) | PARP1TSHRPOLBCYP3A4MAPT | |
| SCHEMBL10458793 | 0.76 | PARP1 (0.64) | PARP1TSHRPOLBCYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003062461-A1 | FMDV LEADER PEPTIDASE ASSAY | AMURA THERPEUTICS LIMITED (GB) | 2003-07-31 | — | — | WO | disclosed |
| US-6455290-B1 | NUCLEOTIDE AND AMINO ACID SEQUENCE OF PROTEIN INVOLVED IN TELOMERES; ANTICARCINOGENIC AGENTS; TREATMENT OF AGE-RELATED DISEASES | PHARMACIA ITALIA S.P.A. (IT) | 2002-09-24 | — | — | US | disclosed |
| WO-2002006240-A1 | SUBSTITUTED 4,9-DIHYDROCYCLOPENTA[IMN] PHENANTHRIDINE-5-ONES, DERIVATIVES THEREOF AND THEIR USES | GUILFORD PHARMACEUTICALS INC. (US) | 2002-01-24 | — | — | WO | disclosed |