Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 3/20 | 0.55 |
| ▸ | AR | P10275 | 8/20 | 0.48 |
| ▸ | PGR | P06401 | 7/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7139757 | 1.00 | SHBG (0.55) | SHBGARPGRNR3C2SLC22A1 | |
| SCHEMBL6569048 | 1.00 | SHBG (0.55) | SHBGARPGRNR3C2SLC22A1 | |
| SCHEMBL6569049 | 1.00 | SHBG (0.55) | SHBGARPGRNR3C2SLC22A1 | |
| SCHEMBL7138348 | 0.86 | SHBG (0.44) | SHBGARPGRNR3C2SLC22A1 | |
| SCHEMBL7138349 | 0.86 | SHBG (0.44) | SHBGARPGRNR3C2SLC22A1 | |
| SCHEMBL6569593 | 0.84 | SHBG (0.65) | SHBGARPGRNR3C2SLC22A1 | |
| SCHEMBL7141591 | 0.84 | SHBG (0.65) | SHBGARPGRNR3C2SLC22A1 | |
| SCHEMBL7141546 | 0.77 | SHBG (0.62) | SHBGARPGRNR3C2SLC22A1 | |
| SCHEMBL6570514 | 0.77 | SHBG (0.62) | SHBGARPGRNR3C2SLC22A1 | |
| SCHEMBL6570215 | 0.75 | SHBG (0.51) | SHBGARPGRNR3C2SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343804-A1 | 14(15)-UNSATURATED 15- AND/OR 16- SUBSTITUTED ANDROGENS WITH MIXED ANDROGEN-PROGESTATIONAL PROFILE | Akzo Nobel N.V. (NL) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002048169-A1 | 14(15)-UNSATURATED 15- AND/OR 16- SUBSTITUTED ANDROGENS WITH MIXED ANDROGEN-PROGESTATIONAL PROFILE | AKZO NOBEL N.V. (NL) | 2002-06-20 | — | — | WO | disclosed |