Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 17/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 15/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 8/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.59 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.59 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.59 |
| ▸ | HRH1 | P35367 | 1/20 | 0.59 |
| ▸ | HTR2B | P41595 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7140049 | 1.00 | CHRM3 (0.60) | CHRM3CHRM2CHRM1KCNH2CHRM4 | |
| SCHEMBL7147345 | 1.00 | CHRM3 (0.60) | CHRM3CHRM2CHRM1KCNH2CHRM4 | |
| Bromide SCHEMBL7151353 | 0.99 | CHRM3 (0.61) | CHRM3CHRM2CHRM1KCNH2CHRM4 | |
| SCHEMBL13716300 | 0.94 | CHRM3 (0.68) | CHRM3CHRM2CHRM1KCNH2CHRM4 | |
| SCHEMBL7145497 | 0.94 | CHRM3 (0.68) | CHRM3CHRM2CHRM1KCNH2CHRM4 | |
| SCHEMBL13716305 | 0.94 | CHRM3 (0.68) | CHRM3CHRM2CHRM1KCNH2CHRM4 | |
| SCHEMBL7145504 | 0.94 | CHRM3 (0.68) | CHRM3CHRM2CHRM1KCNH2CHRM4 | |
| SCHEMBL170999 | 0.94 | CHRM3 (0.68) | CHRM3CHRM2CHRM1KCNH2CHRM4 | |
| Bromide SCHEMBL131394 | 0.93 | CHRM3 (0.69) | CHRM3CHRM2CHRM1KCNH2CHRM4 | |
| Bromide SCHEMBL130614 | 0.93 | CHRM3 (0.69) | CHRM3CHRM2CHRM1KCNH2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1369414-A1 | Enantiomerically pure Arylcycloalkyl hydroxycarboxylic esters, processes for their preparation and their use as modulators of muscarinic receptors | Noe, Christian R. (AT) | 2003-12-10 | — | — | EP | claimed |