Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5406222 | 1.00 | ECE1 (0.33) | ECE1TP53 | |
| SCHEMBL6810715 | 0.71 | GLA (0.36) | ECE1 | |
| SCHEMBL5404053 | 0.71 | ECE1 (0.33) | ECE1 | |
| SCHEMBL5404048 | 0.71 | ECE1 (0.33) | ECE1 | |
| SCHEMBL7144794 | 0.70 | ECE1 (0.41) | ECE1 | |
| SCHEMBL5415653 | 0.70 | ECE1 (0.41) | ECE1 | |
| SCHEMBL5412971 | 0.68 | ECE1 (0.43) | ECE1 | |
| SCHEMBL5407509 | 0.67 | ECE1 (0.42) | ECE1 | |
| SCHEMBL5411627 | 0.65 | ECE1 (0.43) | ECE1 | |
| SCHEMBL5407304 | 0.64 | ECE1 (0.45) | ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303486-A1 | PYRROLIDINE DERIVATIVES AS METALLOPROTEASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-04-23 | — | — | EP | disclosed |
| WO-2002008185-A1 | PYRROLIDINE DERIVATIVES AS METALLOPROTEASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2002-01-31 | — | — | WO | disclosed |