Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.52 |
| ▸ | ERN1 | O75460 | 2/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | PELP1 | Q8IZL8 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL9479039 | 0.89 | VCAM1 (0.56) | VCAM1ERN1HPGDALDH1A1NPSR1 | |
| SCHEMBL11965649 | 0.86 | VCAM1 (0.58) | VCAM1ERN1HPGDALDH1A1NPSR1 | |
| SCHEMBL537223 | 0.84 | ERN1 (0.62) | VCAM1ERN1ARPELP1HPGD | |
| SCHEMBL537387 | 0.81 | VCAM1 (0.52) | VCAM1ERN1ARPELP1HPGD | |
| SCHEMBL7085039 | 0.80 | VCAM1 (0.51) | VCAM1ERN1ARPELP1HPGD | |
| SCHEMBL7085042 | 0.80 | VCAM1 (0.51) | VCAM1ERN1ARPELP1HPGD | |
| SCHEMBL5734347 | 0.79 | VCAM1 (0.68) | VCAM1ERN1HPGDALDH1A1NPSR1 | |
| SCHEMBL3970653 | 0.78 | VCAM1 (0.50) | VCAM1ERN1ARPELP1HPGD | |
| SCHEMBL4133735 | 0.78 | VCAM1 (0.50) | VCAM1ERN1ARPELP1HPGD | |
| SCHEMBL223175 | 0.77 | VCAM1 (0.57) | VCAM1ERN1ARPELP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6509365-B1 | 2-phenylbenzimidazoles and 2-phenylindoles, and production and use thereof | BASF AKTIENGESELLSCHAFT (DE) | 2003-01-21 | — | — | US | disclosed |