Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.51 |
| ▸ | USP2 | O75604 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7140065 | 0.76 | PTGDR2 (0.33) | PTGDR2ALOX15HSD17B10 | |
| SCHEMBL3982874 | 0.76 | PTGDR2 (0.62) | PTGDR2USP2ALOX15ALPLSMN1; SMN2 | |
| SCHEMBL16217687 | 0.75 | PTGDR2 (0.57) | PTGDR2USP2ALOX15ALPLMEN1 | |
| SCHEMBL3982876 | 0.74 | PTGDR2 (0.65) | PTGDR2USP2ALOX15ALPLMEN1 | |
| SCHEMBL13748304 | 0.74 | PTGDR2 (0.64) | PTGDR2USP2ALOX15ALPLTSHR | |
| SCHEMBL29210715 | 0.74 | PTGDR2 (0.56) | PTGDR2USP2ALOX15ALPLTSHR | |
| SCHEMBL399302 | 0.72 | PTGDR2 (0.57) | PTGDR2USP2ALOX15ALPLHPGD | |
| SCHEMBL7717554 | 0.71 | PTGDR2 (0.60) | PTGDR2USP2ALOX15ALPLTSHR | |
| SCHEMBL1542948 | 0.71 | PTGDR2 (0.56) | PTGDR2USP2ALOX15ALPLTSHR | |
| SCHEMBL29426974 | 0.71 | PTGDR2 (0.56) | PTGDR2USP2ALOX15ALPLTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0907646-B1 | DIHYDROBENZOPYRAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | UNIV VANDERBILT (US) | 2003-05-21 | — | — | EP | disclosed |
| US-6110960-A | FOR TREATING ARTHRITIS AND AS ANALGESIC | THE PROCTER & GAMBLE COMPANY (US) | 2000-08-29 | — | — | US | disclosed |