Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 1/20 | 0.37 |
| ▸ | ATP4A | P20648 | 3/20 | 0.33 |
| ▸ | ATP4B | P51164 | 3/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL712468 | 0.77 | NPC1 (0.32) | — | |
| SCHEMBL712121 | 0.77 | APP (0.38) | AGXTATP4AATP4BHSP90AA1HSP90AB1 | |
| Water SCHEMBL713364 | 0.76 | APP (0.37) | AGXTATP4AATP4BHSP90AA1HSP90AB1 | |
| SCHEMBL714517 | 0.72 | PDE10A (0.36) | AGXTATP4AATP4BHSP90AA1HSP90AB1 | |
| SCHEMBL8910240 | 0.71 | AGXT (0.49) | AGXTATP4AATP4BHSP90AA1HSP90AB1 | |
| SCHEMBL29382857 | 0.70 | AGXT (0.66) | AGXTATP4AATP4BHSP90AA1HSP90AB1 | |
| SCHEMBL1060082 | 0.70 | AGXT (0.66) | AGXTATP4AATP4BHSP90AA1HSP90AB1 | |
| Hydrochloric Acid SCHEMBL3247161 | 0.69 | AGXT (0.64) | AGXTATP4AATP4BHSP90AA1HSP90AB1 | |
| SCHEMBL8500701 | 0.67 | AGXT (0.45) | AGXTATP4AATP4BHSP90AA1HSP90AB1 | |
| SCHEMBL3182871 | 0.66 | AGXT (0.44) | AGXTATP4AATP4BHSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124780-B2 | Benzimidazole compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-02-28 | — | — | US | disclosed |
| EP-1870409-B1 | BENZIMIDAZOLE COMPOUNDS | EISAI R&D MAN CO LTD (JP) | 2010-05-12 | — | — | EP | disclosed |
| US-20090203911-A1 | BENZIMIDAZOLE COMPOUND | MIYAZAWA SHUHEI | 2009-08-13 | — | — | US | disclosed |
| US-7425634-B2 | Benzimidazole compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2008-09-16 | — | — | US | disclosed |
| EP-1870409-A1 | BENZIMIDAZOLE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2007-12-26 | — | — | EP | disclosed |
| US-20070015782-A1 | Benzimidazole compound | EISAI CO., LTD. | 2007-01-18 | — | — | US | disclosed |
| US-20070010542-A1 | Benzimidazole compound | EISAI CO., LTD. | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010542-A1 | Benzimidazole compound | HRH2, GIPR, HRH4 | AGXT 1770/4885ATP4A 317/4885ATP4B 1795/4885 |
| US-20090203911-A1 | BENZIMIDAZOLE COMPOUND | HRH2, HRH4, HRH1 | AGXT 1759/4885ATP4A 175/4885ATP4B 1335/4885 |
| US-20070015782-A1 | Benzimidazole compound | HRH2, GIPR, HRH4 | AGXT 1770/4885ATP4A 317/4885ATP4B 1795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.